Killer T cells surround a cancer cell. Credit: NIH

Hans Clevers (Hubrecht Institute) and David Tuveson (Cold Spring Harbor Laboratory), experts in the field of stem cells and organoids, have written a review that summarizes the use of organoids in cancer research and shines a light on prospects for the future.

These mini-organs can be used to study tumor biology, model tumor development, and to test existing and new therapies in a patient specific way.

The main points of the review are explained by Hans Clevers in the attached video.

The was published in the scientific journal Science, on the 6th of June.

Hans Clevers explains the use of human organoids, or mini-organs, to study tumor biology, model tumor development, and to test existing and new therapies in a patient specific way. Credit: © Hubrecht Institute, Video made by Esther Pardijs, Animations made by DEMCON | nymus3D

More information: D. Tuveson at Cold Spring Harbor Laboratory in Cold Spring Harbor, NY el al., "Cancer modeling meets human organoid technology," Science (2019). science.sciencemag.org/cgi/doi … 1126/science.aaw6985

Journal information: Science

Provided by Hubrecht Institute