An international study has discovered a molecule which could form the basis of powerful new anti-malaria drugs. The paper "Quinolone-3-Diarylethers: a new class of drugs for a new era of malaria eradication" has been published ...
Medical research Mar 20, 2013 | 5 / 5 (1) | 1 |
(Medical Xpress)—Researchers in Australia have found that a protein in platelets found naturally in blood has a protective effect against malaria. In their paper published in the journal Science, the team describes how th ...
Medical research Dec 07, 2012 | 5 / 5 (1) | 0 |
(Medical Xpress)—A new study out today reveals that the emergence and spread of a rapidly evolving invasive intestinal disease, that has a significant mortality rate (up to 45%) in infected people in sub-Saharan ...
Genetics Sep 30, 2012 | 5 / 5 (3) | 1 |
(Medical Xpress)—When the parasite responsible for malaria infects human red blood cells, it launches a 48-hour remodeling of the host cells. During the first 24 hours of this cycle, a protein called RESA undertakes the ...
Medical research Aug 30, 2012 | not rated yet | 0 |
An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key ...
Medical research Jul 19, 2012 | 4 / 5 (2) | 0 |
Researchers from the University of Notre Dame's Eck Institute for Global Health developed a "gene chip" to contribute to the identification of malaria drug resistance, an effort that will allow for real-time response in modified ...
Diseases, Conditions, Syndromes Apr 05, 2012 | not rated yet | 0 |
Artemisinin-resistant untreatable malaria increasing rapidly along the Thailand-Myanmar border: study
Evidence that the most deadly species of malaria parasite, Plasmodium falciparum, is becoming resistant to the front line treatment for malaria on the border of Thailand and Myanmar (Burma) is reported in The ...
Diseases, Conditions, Syndromes Apr 05, 2012 | 5 / 5 (2) | 0 |
(Medical Xpress) -- Malaria is a disease caused by parasites passed to humans via the bites of infected mosquitoes. Globally, the disease causes over a million deaths every year, and is especially rife in ...
Medical research Nov 11, 2011 | 4.8 / 5 (16) | 2 |
Using live but weakened malaria parasites as the basis of a vaccine represents a potentially encouraging anti-malaria strategy, according to results of follow-up animal studies performed after the conclusion of a recent clinical ...
Medical research Sep 08, 2011 | not rated yet | 0 |
Melbourne scientists have made the surprise discovery that malaria parasites can 'talk' to each other – a social behaviour to ensure the parasite's survival and improve its chances of being transmitted ...
Medical research May 15, 2013 | not rated yet | 0 |
(Medical Xpress)—The newest public health threat in Africa, scientists have found, is coming from a previously unknown source: the banded mongoose. Leptospirosis, the disease is called. And the banded mongoose ...
Diseases, Conditions, Syndromes May 14, 2013 | not rated yet | 0 |
(HealthDay)—Many pre-term babies suffer recurrent episodes of wheezing. Now, researchers say a common infection is a likely culprit and they may be able to prevent the breathing problems.
Diseases, Conditions, Syndromes May 09, 2013 | not rated yet | 0 |
(Medical Xpress)—Malaria is responsible for about 700,000 deaths annually in sub-Saharan Africa alone, and a team of Texas A&M University researchers is doing their best to help stem this perpetual tide of human suffering.
Genetics May 07, 2013 | not rated yet | 0 |
Gene analysis of malaria parasites has pinpointed western Cambodia as the hotspot of strains that are dangerously resistant to artesiminin, the frontline drug against the disease, scientists said on Sunday.
Genetics Apr 28, 2013 | 5 / 5 (1) | 0
Scientists have discovered how a protein within the malaria parasite is essential to its survival as it develops inside a mosquito. They believe their findings identify this protein as a potential new target for drug treatments ...
Medical research Apr 25, 2013 | not rated yet | 0 |
Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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