Statins not tied to women's gonado-sexual dysfunction

(HealthDay)—Statin use is not associated with higher risk of gonado-sexual dysfunction in women, according to a study published online Nov. 10 in the Journal of Sexual Medicine.

Sayed K. Ali, M.D., from the VA South Texas Health Care System in San Antonio, and colleagues compared the risk of gonado-sexual dysfunction in statin users and nonusers using data from female adult patients (mean age, 58 years) enrolled in the Tricare Prime/Plus San Antonio catchment area. Baseline characteristics were evaluated Oct. 1, 2003, to Sept. 30, 2005, while outcomes (menstrual disorders, menopausal disorders, infertility, and ovarian/sexual dysfunction) were evaluated over a follow-up period from Oct. 1, 2005, to March 1, 2012.

The researchers found that, based on analysis of the propensity score-matched 2,890 statin users and 2,890 nonusers, statin use was not significantly associated with menstrual disorders (odds ratio [OR], 0.97; 95 percent confidence interval [CI], 0.81 to 1.16), menopausal disorders (OR, 0.92; 95 percent CI, 0.83 to 1.02), infertility (OR, 0.79; 95 percent CI, 0.36 to 1.73), or ovarian/sexual dysfunction (OR, 1.18; 95 percent CI, 0.83 to 1.70).

"Statin use was not associated with higher risk of gonado-sexual dysfunction in women," the authors write.