Medical research

First all-human mouse model of inherited prion disease

Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study in the open-access journal PLOS Biology reports a significant advance in the development of mouse ...

Medications

Immunotherapy for bowel cancer could change clinical practice

A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of ...

Neuroscience

Gut microbiome influences ALS outcomes

Harvard University scientists have identified a new gut-brain connection in the neurodegenerative disease amyotrophic lateral sclerosis, or ALS. The researchers found that in mice with a common ALS genetic mutation, changing ...

Genetics

Researchers uncover genetic cause behind glaucoma

New research has identified a genetic mutation linked to a type of glaucoma, known as primary angle-closure glaucoma (PACG), which could open up new avenues for the early detection and treatment of the disease.

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