Advanced imaging pinpoints prostate cancer faster, more accurately

October 5, 2012

It took Wayne Wentzel 14 years, multiple tissue biopsies and travel to four hospitals across multiple states to identify the underlying source of his rising prostate specific antigen (PSA) level. He finally found answers at the University of Cincinnati Cancer Institute.

PSA is calculated based by blood test and used to identify potential signs of prostate cancer. Other issues can contribute to rising PSA—such as enlarged prostate and infection—but the test is the medical community's No. 1 tool for

On a mission to find answers, Wentzel's son-in-law—a Georgia radiologist—found Cincinnati-based radiologist Sadhna Verma, MD. She leads an innovative prostate imaging program based at UC Health University Hospital that utilizes both and 3T spectroscopy imaging to more accurately diagnose prostate cancer before invasive measures are taken. 

"MR imaging has shown to improve detection and accuracy of staging of prostate cancer in patients with prostate cancer," says Verma, a UC associate professor of radiology and UC Health radiologist. "Adding functional sequences gives us biochemical clues in addition to anatomic data to help us pinpoint cancers in the prostate gland that often go undetected otherwise."    

Wentzel, a 69-year-old retired pastor from Michigan, began experiencing a rising PSA in 1998. Before arriving in Cincinnati, he had undergone eight that resulted in the removal of 52 tissue samples —all were negative for cancer.

"The biopsies were painful and got me nowhere. The 3T multi-parametric prostate MRI with scans at UC came back to show a mass in my prostate immediately. Following this, I had an MRI-guided biopsy that confirmed 7 prostate cancer," recalls Wentzel.

He traveled back home to Ann Arbor, Mich., to undergo robotic closer to home in August 2012. 

"I can finally focus on enjoying my retirement without worrying about that rising PSA. I exercise daily to keep my energy up and take the boat out any opportunity I get," he says. 

About the Prostate Imaging Program 
In partnership with UC Health, the UC Cancer Institute offers comprehensive evaluation of the prostate gland that provided both anatomic and biochemical information about the gland.

"Prostate cancer treatment is determined primarily by the stage of disease and whether cancer is confined within the prostate capsule or has extended beyond the prostate gland," explains Verma, who is part of the multidisciplinary genitourinary cancer team at the UC Cancer Institute. "Men have several choices when it comes to treatment. Accuracy of staging is critical for choosing the approach that is right for each individual." 

Explore further: When rising PSA means prostate cancer is in patient's future

More information: Prostate imaging services: www.med.uc.edu/radiology/resea … 20Program/Index.html

Related Stories

When rising PSA means prostate cancer is in patient's future

May 18, 2011
A man's rising PSA (prostate-specific antigen) level over several years – which had been seen as a possible warning sign of prostate cancer – has recently come under fire as a screening test because it sometimes ...

PSA test valuable in predicting biopsy need, low-risk prostate cancer

October 21, 2011
The prostate-specific antigen test, commonly known as the PSA test, is valuable in predicting which men should have biopsies and which are likely to be diagnosed with low-risk prostate cancer, a Mayo Clinic study has found. ...

New prostate cancer test gives more accurate diagnosis

April 6, 2011
In a large multi-center clinical trial, a new PSA test to screen for prostate cancer more accurately identified men with prostate cancer -- particularly the aggressive form of the disease -- and substantially reduced false ...

New imaging agent has an appetite for dangerous prostate tumors

December 8, 2011
Non-invasive imaging detects prostate cancer earlier than ever before, but can't accurately distinguish between malignant and benign disease. According to Lawson Health Research Institute's Drs. John Lewis and Len Luyt, a ...

Cancer biomarker -- detectable by blood test -- could improve prostate cancer detection

August 8, 2011
A new study supports the use of a DNA-based "biomarker" blood test as a complement to the prostate-specific antigen (PSA) test currently offered to screen men for prostate cancer. University of Cincinnati (UC) researchers ...

Genetic test may reduce need for repeat biopsy for prostate cancer

July 18, 2012
Karim Kader, MD, PhD, associate clinical professor at the UC San Diego School of Medicine, together with a team of researchers from Wake Forest University School of Medicine, have developed a genetic test to predict a man’s ...

Recommended for you

Study suggests colon cancer cells carry bacteria with them when they metastasize

November 24, 2017
(Medical Xpress)—A team of researchers working at Harvard University has found evidence that suggests a certain type of bacteria found in colon cancer tumors makes its way to tumors in other body parts by traveling with ...

Promising new treatment for rare pregnancy cancer leads to remission in patients

November 24, 2017
An immunotherapy drug can be used to cure women of a rare type of cancer arising from pregnancy when existing treatments have failed.

Researchers unravel novel mechanism by which tumors grow resistant to radiotherapy

November 23, 2017
A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development. The discovery ...

African Americans face highest risk for multiple myeloma yet underrepresented in research

November 23, 2017
Though African-American men are three times more likely to be diagnosed with multiple myeloma, a type of blood cancer, most scientific research on the disease has been based on people of European descent, according to a study ...

Encouraging oxygen's assault on iron may offer new way to kill lung cancer cells

November 22, 2017
Blocking the action of a key protein frees oxygen to damage iron-dependent proteins in lung and breast cancer cells, slowing their growth and making them easier to kill. This is the implication of a study led by researchers ...

One-size treatment for blood cancer probably doesn't fit all, researchers say

November 22, 2017
Though African-American men are three times more likely to be diagnosed with a blood cancer called multiple myeloma, most scientific research on the disease has been based on people of European descent, according to a study ...

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

PeterD
1 / 5 (1) Oct 05, 2012
Anyone who thinks a PSA test means anything is an idiot.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.