Safety, efficacy of at-home laser for periobital wrinkles studied

October 24, 2012
Safety, efficacy of at-home laser for periobital wrinkles studied
A handheld nonablative fractional laser is safe and seems effective for home use for treating periorbital wrinkles, according to a study published in the November issue of the Journal of the American Academy of Dermatology.

(HealthDay)—A handheld nonablative fractional laser is safe and seems effective for home use for treating periorbital wrinkles, according to a study published in the November issue of the Journal of the American Academy of Dermatology.

James Leyden, M.D., from the Skin Study Center in Broomall, Penn., and colleagues conducted a multicenter trial consisting of two clinical studies in which 124 subjects performed at-home treatment of periorbital wrinkles using a handheld nonablative fractional . Both studies comprised an active treatment phase, including daily treatments, and twice-weekly treatments in a maintenance phase. Ninety subjects were followed through completion of the maintenance phase and 36 were followed for five months after its completion. An in-person investigator assessment, independent blinded review, and subject self-assessment were used to evaluate treatment.

The researchers found that patients were able to follow instructions for safely using the laser, with good compliance to the protocol, and treatments were well tolerated. Independent blinded evaluations showed an improvement in the Fitzpatrick Wrinkle Scale score by one or more grades in 90 percent of subjects at the end of the active phase and in 79 percent at the end of the maintenance phase. Transient posttreatment erythema was the most prevalent side effect.

"In sum, the test device and at-home was demonstrated to have a favorable safety profile and to be effective at reducing the appearance of periorbital ," the authors write. "Subject compliance was high, treatments were well tolerated, and side effects were minimal and transient."

Two authors disclosed financial ties to Palomar Medical Technologies, which funded the study and manufactures the device used in the study.

Explore further: At-home diode laser effective for permanent hair reduction

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

At-home diode laser effective for permanent hair reduction

August 22, 2012
(HealthDay) -- Eight treatments with a home-use diode laser provide effective and safe permanent hair reduction one year after the last treatment, according to research published in the September issue of Lasers in Surgery ...

Pulsed dye laser effective on port-wine stains in infants

February 28, 2012
(HealthDay) -- Pulsed dye laser (PDL) treatment at two-, three-, and four-week intervals is effective for infants with facial port-wine stains (PWS), with minimal short-term side effects, according to a study published online ...

Dual mode laser therapy effectively treats acne vulgaris

March 27, 2012
(HealthDay) -- A series of Nd:YAG laser treatments effectively and rapidly reduces both inflammatory and noninflammatory acne vulgaris lesions, according to a study published in the April issue of the Journal of the American ...

Recommended for you

Single blood test screens for eight cancer types

January 18, 2018
Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

How cancer metastasis happens: Researchers reveal a key mechanism

January 18, 2018
Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial ...

Researchers find a way to 'starve' cancer

January 18, 2018
Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital ...

The pill lowers ovarian cancer risk, even for smokers

January 18, 2018
(HealthDay)—It's known that use of the birth control pill is tied to lower odds for ovarian cancer, but new research shows the benefit extends to smokers or women who are obese.

These foods may up your odds for colon cancer

January 18, 2018
(HealthDay)—Chowing down on red meat, white bread and sugar-laden drinks might increase your long-term risk of colon cancer, a new study suggests.

Modular gene enhancer promotes leukemia and regulates effectiveness of chemotherapy

January 18, 2018
Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer. Scientists from the German Cancer Research ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.