March 21, 2024

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Mortality among low-risk differentiated thyroid cancer survivors in the US

Flowchart of the study population. Credit: Thyroid (2023). DOI: 10.1089/thy.2023.0449
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Flowchart of the study population. Credit: Thyroid (2023). DOI: 10.1089/thy.2023.0449

A new study has shown that overall and cause-specific mortality rates in individuals in the U.S. with low-risk differentiated thyroid cancer (DTC) are low. The study is published in Thyroid.

Cari Kitahara, Ph.D., from the National Cancer Institute, National Institutes of Health, and co-authors identified 51,854 individuals diagnosed with first primary DTC at low risk of recurrence and compared observed in DTC patients with expected rates in the matched U.S. general population.

Thyroid cancer accounted for only 4.3% of deaths. The most common causes of death were malignancies (other than ) and .

"In brief, we observed that these patients experienced lower rates of mortality overall and from most other causes compared with the general population, consistent with previous studies," stated the investigators. "Our study is unique in that it was restricted to survivors of low-risk DTC and included all ages at diagnosis, a longer duration of follow-up compared with previous studies, and a comprehensive investigation of specific causes of death."

More information: Thi-Van-Trinh Tran et al, All-Cause and Cause-Specific Mortality Among Low-Risk Differentiated Thyroid Cancer Survivors in the United States, Thyroid (2023). DOI: 10.1089/thy.2023.0449

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