Archive: 08/04/2013
AKT inhibitor AZD5363 well tolerated, yielded partial response in patients with advanced solid tumors
The investigational drug AZD5363, which has shown activity in preclinical studies, was well tolerated in humans, and two patients with advanced solid tumors showed partial response, according to data presented at the AACR ...
Apr 8, 2013
Neuroscientists show 'jumping genes' may contribute to aging-related brain defects
As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, ...
Apr 8, 2013
First trial—investigating magic mushrooms as a treatment for depression—delayed by UK and EU regulations
The world's first clinical trial to explore the use of the hallucinogenic ingredient in magic mushrooms to treat depression is being delayed due to the UK and EU rules on the use of illegal drugs in research.
Apr 8, 2013
KDM1 may represent a new therapeutic target for glioma
Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...
Apr 8, 2013
More accurate markers identified for detecting response to epigenetic drugs for myelodysplastic syndromes
Researchers have identified and validated two DNA methylation markers that could help physicians to more accurately determine a patient's response to epigenetic drugs for treatment of myelodysplastic syndromes (MDS), according ...
Apr 8, 2013
Black women have worse breast cancer mortality regardless of cancer subtype
Black women with breast cancer had significantly worse survival compared with other racial and ethnic groups across cancer subtypes, which suggests that the survival differences are not solely attributable to the fact that ...
Apr 8, 2013
New research shows how our bodies interact with our minds in response to fear and other emotions
New research has shown that the way our minds react to and process emotions such as fear can vary according to what is happening in other parts of our bodies.
Apr 8, 2013
BRAF mutation less common among patients with melanoma in Ireland
The BRAF mutation believed to drive disease in about half of patients with melanoma was found to occur at a significantly lower frequency in patients with melanoma in Ireland, according to data presented at the AACR Annual ...
Apr 8, 2013