Medical research

How microglia contribute to Alzheimer's disease

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience. A new study from MIT shows how a type of cells called ...

Alzheimer's disease & dementia

DNA vaccine reduces both toxic proteins linked to Alzheimer's

A DNA vaccine tested in mice reduces accumulation of both types of toxic proteins associated with Alzheimer's disease, according to research that scientists say may pave the way to a clinical trial.

Alzheimer's disease & dementia

Racial differences in Alzheimer's disease unveiled

African-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why because studies investigating the underlying causes of illness have historically drawn from a nearly all-white ...

Genetics

Newly discovered protein connected to Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, ...

Alzheimer's disease & dementia

Brain cholesterol regulates Alzheimer's plaques, study reveals

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

Alzheimer's disease & dementia

A new culprit of cognitive decline in Alzheimer's disease

It has long been known that patients with Alzheimer's disease have abnormalities in the vast network of blood vessels in the brain. Some of these alterations may also contribute to age-related cognitive decline in people ...

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