Autoimmune Diseases

Transmural control of plaque formation

In atherosclerosis, fatty "plaques" form in the inner layer of arteries. As an LMU team now shows, specialized lymphoid organs found on the outer arterial wall adjacent to plaques help to restrain the inflammation that boosts ...

Jun 17, 2015
popularity2 comments 0

Keeping a lid on inflammation

Regulatory T cells (Treg cells) are part of the system of checks and balances that prevents the immune response from going overboard and causing autoimmune disease. Although critically important for shaping the immune response ...

Jun 17, 2015
popularity56 comments 0

Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

How to become a T follicular helper cell

Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the ...

HVTN 505 vaccine induced antibodies nonspecific for HIV

A study by researchers at the National Institute of Allergy and Infectious Diseases and Duke University helps explain why the candidate vaccine used in the HVTN 505 clinical trial was not protective against HIV infection ...

A cheaper, high-performance prosthetic knee

In the last two decades, prosthetic limb technology has grown by leaps and bounds. Today, the most advanced prostheses incorporate microprocessors that work with onboard gyroscopes, accelerometers, and hydraulics to enable ...

Take a trip through the brain (w/ Video)

A new imaging tool developed by Boston scientists could do for the brain what the telescope did for space exploration. In the first demonstration of how the technology works, published July 30 in the journal Cell, the researchers ...