Autoimmune Diseases

Researchers reverse bone loss in immune disorder

Patients with leukocyte adhesion deficiency, or LAD, suffer from frequent bacterial infections, including the severe gum disease known as periodontitis. These patients often lose their teeth early in life.

Mar 26, 2014
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Beta-catenin alters T cells in lasting and harmful ways

Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in the February 26, 2014, issue ...

Feb 26, 2014
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Sensitive balance in the immune system

Apoptosis is used by cells that are changed by disease or are simply not needed any longer to eliminate themselves before they become a hazard to the body—on a cellular level, death is part of life. Disruption ...

Apr 11, 2014
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Immunology: White blood cells show their stripes

For the human immune system to work effectively, the body must be able to distinguish invading pathogens, such as fungi and bacteria, from its own healthy tissue. A group of white blood cells known as dendritic ...

Aug 28, 2013
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Latest Spotlight News

New compounds reduce debilitating inflammation

Six Case Western Reserve scientists are part of an international team that has discovered two compounds that show promise in decreasing inflammation associated with diseases such as ulcerative colitis, arthritis and multiple ...