Colorectal Cancer

How mouth microbes may worsen colorectal cancer

Bacteria commonly found in the mouth have been recently shown to worsen colorectal cancer in animals, but it has not been clear how these microbes make their way to the gut in the first place. A study published August 10 ...

Aug 10, 2016
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Molecule prevents effect of chemotherapy

Annually about 2000 Danish patients with colorectal cancer are treated with chemotherapy. Today, a range of different chemotherapeutic regimens are available. However, deciding which regimen to use is not easy. Unfortunately, ...

Aug 16, 2016
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New cancer type with PIK3CA mutations

A newly defined type of colorectal and endometrial cancer involves at least two somatic mutations in the mismatch repair genes (MMR): MLH1, MSH2, MSH6, PMS2. This double somatic MMR cancer has no germline mutations in the ...

Aug 16, 2016
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Increasing prevalence of obesity in cancer survivors

(HealthDay)—From 1997 to 2014 the estimated rate of annual increase in obesity prevalence was higher for adults with a history of cancer, according to a study published online July 25 in the Journal of Clinical Oncology.

Aug 01, 2016
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Not all tumor cells are equal

A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program (PEBC) of Bellvitge Biomedical Research Institute (IDIBELL), ICREA researcher and Professor of Genetics at University of Barcelona ...

Aug 18, 2016
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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.

Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.

Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.

This text uses material from Wikipedia licensed under CC BY-SA

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