Surgery

Reasons to be a living kidney donor

Nearly 100,000 people in the U.S. are on the waiting list for kidney transplant, according to the Organ Procurement and Transplantation Network. Finding a donor kidney that is compatible and matches the right blood and tissue ...

Medications

Curbing the price of novel diabetes and obesity medications

For years, Kasia Lipska, MD, MHS, associate professor of medicine (endocrinology) at Yale School of Medicine (YSM), has been advocating for affordable pricing of insulin, an essential —and sometimes lifesaving—drug for ...

Medications

Experimental drug shields pancreas from type 1 diabetes attack

Scientists at Johns Hopkins Medicine say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' ...

Diabetes

Inhaled insulin could improve lives of patients with diabetes

Millions of people around the world live with diabetes mellitus. Many of them have medication and specific dietary management approaches to help them maintain stable blood sugar levels. However, recent innovations, such as ...

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Diabetes mellitus, often simply referred to as diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).

There are three main types of diabetes:

Other forms of diabetes mellitus include congenital diabetes, which is due to genetic defects of insulin secretion, cystic fibrosis-related diabetes, steroid diabetes induced by high doses of glucocorticoids, and several forms of monogenic diabetes.

All forms of diabetes have been treatable since insulin became available in 1921, and type 2 diabetes may be controlled with medications. Both type 1 and 2 are chronic conditions that usually cannot be cured. Pancreas transplants have been tried with limited success in type 1 DM; gastric bypass surgery has been successful in many with morbid obesity and type 2 DM. Gestational diabetes usually resolves after delivery. Diabetes without proper treatments can cause many complications. Acute complications include hypoglycemia, diabetic ketoacidosis, or nonketotic hyperosmolar coma. Serious long-term complications include cardiovascular disease, chronic renal failure, retinal damage. Adequate treatment of diabetes is thus important, as well as blood pressure control and lifestyle factors such as smoking cessation and maintaining a healthy body weight.

Globally as of 2010 it is estimated that there are 285 million people diabetes with type 2 making up about 90% of the cases.

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