Esophageal Cancer

Researchers use sugar to halt esophageal cancer in its tracks

Scientists working at the Medical Research Council have identified changes in the patterns of sugar molecules that line pre-cancerous cells in the esophagus, a condition called Barrett's dysplasia, making it much easier to ...

Cancer created Jan 15, 2012 | popularity 4.4 / 5 (5) | comments 0 | with audio podcast

Pill-sized device provides rapid, detailed imaging of esophageal lining

Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine ...

Medical research created Jan 13, 2013 | popularity 4 / 5 (5) | comments 2 | with audio podcast

Some bacteria may protect against disease caused by stomach infection

Half of the world's human population is infected with the stomach bacteria called Helicobacter pylori, yet it causes disease in only about 10 percent of those infected. Other bacteria living in the stomach may be a key fa ...

Immunology created Mar 12, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Low-dose aspirin stymies proliferation of two breast cancer lines, study finds

Regular use of low-dose aspirin may prevent the progression of breast cancer, according to results of a study by researchers at the Veterans Affairs Medical Center in Kansas City, Mo., and the University of Kansas Medical ...

Cancer created Apr 21, 2013 | popularity 4.7 / 5 (3) | comments 0

Ulcer-causing bacteria tamed by defect in cell-targeting ability

Without the ability to swim to their targets in the stomach, ulcer-causing bacteria do not cause the inflammation of the stomach lining that leads to ulcers and stomach cancer, according to a new study by researchers at the ...

Medical research created Nov 21, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study reveals origins of esophageal cancer

(Medical Xpress) -- Researchers at Columbia University Medical Center (CUMC) have identified the critical early cellular and molecular events that give rise to a type of esophageal cancer called esophageal ...

Cancer created Jan 17, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Relieving the effects of surgery with hypnosis

When Don Gotler was undergoing two procedures preparing him for treatment for his esophageal cancer last year, his doctor asked if he wanted to take part in the hospital's new hypnotherapy program. Combined with anesthesia, ...

Other created Jul 19, 2011 | popularity 5 / 5 (1) | comments 0

Genetic link to Barrett's esophagus, esophageal cancer discovered

Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux ...

Genetics created Jul 26, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

For some surgeries, more is better when choosing hospitals

Are you scheduled for heart bypass surgery or weight loss surgery? You might want to find out just how frequently different hospitals in your area are performing those procedures before deciding where to go. ...

Other created Sep 01, 2011 | popularity 5 / 5 (1) | comments 0

Alcohol metabolism causes DNA damage and triggers a breast cancer-related DNA damage response

Alcohol is known to be carcinogenic to humans in the upper aerodigestive tract, liver, colorectum, and the female breast. Evidence suggests that acetaldehyde, the primary metabolite of alcohol, plays a major role in alcohol-related ...

Health created Sep 15, 2011 | popularity 5 / 5 (1) | comments 0

Risk of esophageal cancer in patients with Barrett’s esophagus

(Medical Xpress) -- A new study published in the New England Journal of Medicine reveals that the risk of patients with Barrett’s esophagus developing adenocarcinoma of the esophagus are not as high as once originally though ...

Cancer created Oct 14, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

Social media has role in delivery of healthcare but patients should proceed with caution

Social networking sites like Facebook and YouTube can be powerful platforms to deliver and receive healthcare information, especially for patients and caregivers who are increasingly going online to connect and share experiences ...

Health created Oct 31, 2011 | popularity 5 / 5 (1) | comments 0

Pre-op treatments boost survival for esophageal cancer patients: study

(HealthDay) -- Patients with esophageal cancer who receive chemotherapy and radiation before surgery have better outcomes, Dutch researchers report.

Cancer created May 30, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Scientists find new role for P53 genetic mutation -- initiation of prostate cancer

A team of UC Davis investigators has found that a genetic mutation may play an important role in the development of prostate cancer. The mutation of the so-called p53 (or Tp53) gene was previously implicated in late disease ...

Cancer created Jun 07, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Other stomach microbiota modulate resistance to H. pylori-driven ulcers

Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of pri ...

Immunology created Mar 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast


Esophageal cancer (or oesophageal cancer) is malignancy of the esophagus. There are various subtypes, primarily squamous cell cancer (approx 90-95% of all esophageal cancer worldwide) and adenocarcinoma (approx. 50-80% of all esophageal cancer in the United States). Squamous cell cancer arises from the cells that line the upper part of the esophagus. Adenocarcinoma arises from glandular cells that are present at the junction of the esophagus and stomach.

Esophageal tumors usually lead to dysphagia (difficulty swallowing), pain and other symptoms, and are diagnosed with biopsy. Small and localized tumors are treated surgically with curative intent. Larger tumors tend not to be operable and hence are treated with palliative care; their growth can still be delayed with chemotherapy, radiotherapy or a combination of the two. In some cases chemo- and radiotherapy can render these larger tumors operable. Prognosis depends on the extent of the disease and other medical problems, but is fairly poor.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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