Esophageal Cancer

Discovery of the genes responsible for esophageal cancer

A Japanese research group has discovered the genetic mutations responsible for esophageal cancer frequently found among Japanese people. They base their discovery on a genomic analysis of 144 Japanese esophageal cancer patients, ...

Jul 15, 2016
popularity44 comments 0

Esophageal cancer (or oesophageal cancer) is malignancy of the esophagus. There are various subtypes, primarily squamous cell cancer (approx 90-95% of all esophageal cancer worldwide) and adenocarcinoma (approx. 50-80% of all esophageal cancer in the United States). Squamous cell cancer arises from the cells that line the upper part of the esophagus. Adenocarcinoma arises from glandular cells that are present at the junction of the esophagus and stomach.

Esophageal tumors usually lead to dysphagia (difficulty swallowing), pain and other symptoms, and are diagnosed with biopsy. Small and localized tumors are treated surgically with curative intent. Larger tumors tend not to be operable and hence are treated with palliative care; their growth can still be delayed with chemotherapy, radiotherapy or a combination of the two. In some cases chemo- and radiotherapy can render these larger tumors operable. Prognosis depends on the extent of the disease and other medical problems, but is fairly poor.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Smartphone exercises for a better mood

Brief, directed smartphone exercises can help quickly improve our mood. This is the latest finding from psychologists at the University of Basel and their international colleagues, reported in the journal Frontiers in Psychology.

The brain's super-sensitivity to curbs

Humans rely on boundaries like walls and curbs for navigation, and Johns Hopkins University researchers have pinpointed the areas of the brain most sensitive to even the tiniest borders.