Foot And Mouth Disease

Foot-and-mouth disease or hoof-and-mouth disease (Aphtae epizooticae) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever for two or three days, followed by blisters inside the mouth and on the feet that may rupture and cause lameness.

Foot-and-mouth disease is a severe plague for animal farming, since it is highly infectious and can be spread by infected animals through aerosols, through contact with contaminated farming equipment, vehicles, clothing or feed, and by domestic and wild predators. Its containment demands considerable efforts in vaccination, strict monitoring, trade restrictions and quarantines, and occasionally the elimination of millions of animals.

Susceptible animals include cattle, water buffalo, sheep, goats, pigs, antelope, deer, and bison. It has also been known to infect hedgehogs, elephants, llama, and alpaca may develop mild symptoms, but are resistant to the disease and do not pass it on to others of the same species. In laboratory experiments, mice and rats and chickens have been successfully infected by artificial means, but it is not believed that they would contract the disease under natural conditions. Humans are very rarely affected.

The virus responsible for the disease is a picornavirus, the prototypic member of the genus Aphthovirus. Infection occurs when the virus particle is taken into a cell of the host. The cell is then forced to manufacture thousands of copies of the virus, and eventually bursts, releasing the new particles in the blood. The virus is highly variable, which limits the effectiveness of vaccination.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Location of body fat can increase hypertension risk

People with fat around their abdominal area are at greater risk of developing hypertension when compared to those with similar body mass index but fat concentrations elsewhere on the body, according to a ...

Carcinogenic role of a protein in liver decoded

The human protein EGFR controls cell growth. It has mutated in case of many cancer cells or exists in excessive numbers. For this reason it serves as a point of attack for target-oriented therapies. A study ...

A nucleotide change could initiate fragile X syndrome

Researchers reveal how the alteration of a single nucleotide—the basic building block of DNA—could initiate fragile X syndrome, the most common inherited form of intellectual disability. The study appears ...

Neurons in human skin perform advanced calculations

Neurons in human skin perform advanced calculations, previously believed that only the brain could perform. This is according to a study from Umeå University in Sweden published in the journal Nature Ne ...

Training your brain to prefer healthy foods

It may be possible to train the brain to prefer healthy low-calorie foods over unhealthy higher-calorie foods, according to new research by scientists at the Jean Mayer USDA Human Nutrition Research Center ...