The inherited gene that leads to Huntington's disease has been found to affect brain development from an early age, even though most patients don't develop symptoms of the disease until they are between the ages of 30 and ...
Sep 3, 2018
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A new test developed by UBC researchers allows physicians to measure the effects of gene silencing therapy in Huntington's disease and will support the first human clinical trial of a drug that targets the genetic cause of ...
Aug 7, 2015
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A new drug screening technology developed at the Harvard T.H. Chan School of Public Health has identified a new potential anti-diabetes compound—and a powerful way to quickly test whether other molecules can have a positive ...
Jun 17, 2015
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Transgenic Huntington's disease monkeys show similarity to humans with Huntington's in their progressive neurodegeneration and decline of motor control, scientists from Yerkes National Primate Research Center, Emory University, ...
May 12, 2015
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By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder. The new findings ...
Jan 5, 2015
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Famine, drug abuse and even stress can "silence" certain genes, causing health problems in generations to come. Now scientists are wondering—could therapies that change gene expression in parents help their children?
Dec 22, 2014
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Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's disease.
Nov 25, 2014
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Researchers from the RIKEN Brain Science Institute in Japan, in collaboration with Juntendo University and the Japan Science and Technology Agency, have discovered that a cell receptor widely involved in intracellular calcium ...
Sep 8, 2014
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Creating induced pluripotent stem cells or iPS cells allows researchers to establish "disease in a dish" models of conditions ranging from Alzheimer's disease to diabetes. Scientists at Yerkes National Primate Research Center ...
Sep 5, 2014
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It has been more than 20 years since scientists discovered that mutations in the gene huntingtin cause the devastating progressive neurological condition Huntington's disease, which involves involuntary movements, emotional ...
Aug 12, 2014
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