Lynch Syndrome
Prostate cancer risk rises in men with inherited genetic condition
Men with an inherited genetic condition called Lynch syndrome face a higher lifetime risk of developing prostate cancer and appear to develop the disease at an earlier age, according to a new study led by ...
Cancer
Apr 01, 2013 |
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Genomic screening to detect preventable rare diseases in healthy people
Experts from the UNC School of Medicine and the UNC Gillings School of Global Public Health propose that screening healthy adults for preventable diseases such as colorectal cancer, breast cancer, and several catastrophic ...
Genetics
Mar 06, 2013 |
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Study revises colorectal cancer risk down and other cancer risks up for women with Lynch Syndrome
Lynch Syndrome is a heritable genetic mutation that causes colorectal, endometrial and other cancers. A cooperative study that included the University of Colorado Cancer Center, published in this month's issue of the Journal of ...
Cancer
Feb 26, 2013 |
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Researchers develop clinical screening program for no.1 genetic cause of colon cancer
(Medical Xpress)—Cleveland Clinic researchers have found that colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome, the most common hereditary, adult-onset cause of colorectal cancer, ...
Cancer
Feb 14, 2013 |
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Spanish researchers develop new method to diagnose hereditary breast and ovarian cancer
Researchers of the Catalan Institute of Oncology (ICO) at the Bellvitge Biomedical Research Institute (IDIBELL) have developed and validated a new method to diagnose hereditary breast and ovarian cancer syndrome based on ...
Cancer
Jan 16, 2013 |
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Genetic CRC risk likely mediated by differential adenoma risk
(HealthDay)—Much of the genetic risk for colorectal cancer (CRC) in the general population is mediated by differential adenoma risk, according to research published in the January issue of Gastroenterology.
Cancer
Jan 10, 2013 |
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Snack attack: Eating unhealthy snack foods may affect cancer risk in patients with Lynch syndrome
A new analysis has found that loading up on snack foods may increase cancer risk in individuals with an inborn susceptibility to colorectal and other cancers. Published early online in CANCER, a peer-reviewed journal of the ...
Cancer
Dec 17, 2012 |
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Genetic test results for Lynch syndrome improved with new computer program
Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance." This can be a problem, as people with ...
Cancer
Nov 01, 2012 |
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Study identifies strategy for improved screening for type of hereditary colorectal cancer
In a comparison of strategies to identify individuals with Lynch syndrome, the most common form of hereditary colorectal cancer (CRC), caused by mutations in certain genes (DNA mismatch repair [MMR] genes), universal tumor ...
Cancer
Oct 16, 2012 |
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Researchers find that not all patients will pay for genetic testing
More than one-fifth of people who have received referrals to test for cancer-causing genes say they will only undergo testing if their insurance covers the cost—just as more insurers are instituting cost-sharing for ...
Cancer
Jun 01, 2012 |
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Prevalence of screening for Lynch syndrome varies
(HealthDay) -- Screening for Lynch syndrome, the most common form of inherited colorectal cancer, after a colorectal cancer diagnosis is common at comprehensive cancer centers but not community hospitals, ...
Cancer
Feb 24, 2012 |
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First prospective analysis links breast and pancreatic cancer risk with Lynch syndrome
A new prospective study of patients with Lynch syndrome – an inherited disorder of cancer susceptibility caused by mutations in specific DNA repair genes – provides the first strong evidence that people with Lynch ...
Cancer
Feb 13, 2012 |
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Scientists prove regular aspirin intake halves cancer risk
Scientists including those from Queen's University have discovered that taking regular aspirin halves the risk of developing hereditary cancers.
Cancer
Oct 28, 2011 |
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UT Southwestern program identifies families at high risk for colorectal cancer
UT Southwestern Medical Center has developed a new lifesaving genetic screening program for families at high risk of contracting colorectal cancer, a deadly yet highly preventable form of cancer.
Cancer
Sep 01, 2011 |
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Study: New process that can save at-risk cancer patients is effective and significantly less costly
People at risk for a certain form of colon and other types of cancer may soon have a better chance at surviving or even avoiding the diseases, thanks to a new study done by the Intermountain Clinical Genetics Institute at ...
Cancer
Aug 16, 2011 |
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Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair.
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