Mad Cow Disease
Hitting 'reset' in protein synthesis restores myelination, suggests new treatment for misfolded protein diseases
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Medical research Apr 26, 2013 | 4.3 / 5 (4) | 0 |
Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations ...
Medical research Apr 03, 2013 | 5 / 5 (5) | 1 |
Most commonly associated with such maladies as "mad cow disease" and Creutzfeldt-Jakob disease, prions are increasingly recognized for their ability to induce potentially beneficial traits in a variety of organisms, yeast ...
Medical research Mar 28, 2013 | 5 / 5 (1) | 0 |
Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania ...
Neuroscience Mar 15, 2013 | not rated yet | 0
Rapid hearing loss in both ears may be a symptom of the rare but always-fatal Creutzfeldt-Jakob Disease and should be considered a reason for clinicians to test for the disorder.
Neuroscience Mar 14, 2013 | not rated yet | 0
A few years ago it was found that certain proteins, the prions, when defective are dangerous, as they are involved in neurodegenerative syndromes such as the Creutzfeldt-Jakob and the Alzheimer diseases. ...
Medical research Feb 14, 2013 | 4.7 / 5 (3) | 0 |
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Other Feb 12, 2013 | not rated yet | 0
A new study found no evidence to support concerns that abnormal neurodegenerative disease proteins are "infectious" or transmitted from animals to humans or from one person to another.
Alzheimer's disease & dementia Feb 04, 2013 | 3.7 / 5 (3) | 1 |
An Irish meat processor recalled 10 million burgers Wednesday from supermarkets across Ireland and Britain amid fears that many could contain horsemeat, a discovery that poses no danger to public health but ...
Health Jan 16, 2013 | not rated yet | 0
In a recent publication, researchers of the Computational Biology group at the Luxembourg Centre for Systems Biomedicine showed that neuro-inflammation plays a crucial role in initiating prion disease.
Parkinson's & Movement disorders Nov 29, 2012 | 5 / 5 (1) | 0
(Medical Xpress)—A simple blood test for Creutzfeldt-Jakob Disease and Mad Cow disease is a step closer, following a breakthrough by medical researchers at the University of Melbourne.
Diseases, Conditions, Syndromes Sep 12, 2012 | not rated yet | 0 |
(Medical Xpress) -- Many of us are familiar with prion disease from its most startling and unusual incarnationsthe outbreaks of mad cow disease (bovine spongiform encephalopathy) that created a crisis in ...
Diseases, Conditions, Syndromes Aug 10, 2012 | 5 / 5 (4) | 0 |
(AP) The U.S. Department of Agriculture says a California Holstein discovered in April with mad cow disease was an isolated case and posed no threat to the food supply.
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Medical research Jul 20, 2012 | 5 / 5 (1) | 0 |
Bovine spongiform encephalopathy (BSE, or "mad cow disease") is a fatal disease in cattle that causes portions of the brain to turn sponge-like. This transmissible disease is caused by the propagation of a misfolded form ...
Diseases, Conditions, Syndromes Jul 09, 2012 | 5 / 5 (1) | 0
Bovine spongiform encephalopathy (BSE), commonly known as mad-cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord. BSE has a long incubation period, about 30 months to 8 years, usually affecting adult cattle at a peak age onset of four to five years, all breeds being equally susceptible. In the United Kingdom, the country worst affected, more than 180,000 cattle have been infected and 4.4 million slaughtered during the eradication program.
The disease may be most easily transmitted to human beings by eating food contaminated with the brain, spinal cord or digestive tract of infected carcasses. However, it should also be noted that the infectious agent, although most highly concentrated in nervous tissue, can be found in virtually all tissues throughout the body, including blood. In humans, it is known as new variant Creutzfeldt–Jakob disease (vCJD or nvCJD), and by October 2009, it had killed 166 people in the United Kingdom, and 44 elsewhere Between 460,000 and 482,000 BSE-infected animals had entered the human food chain before controls on high-risk offal were introduced in 1989.
A British inquiry into BSE concluded that the epizootic was caused by cattle, who are normally herbivores, being fed the remains of other cattle in the form of meat and bone meal (MBM), which caused the infectious agent to spread. The cause of BSE may be from the contamination of MBM from sheep with scrapie that were processed in the same slaughterhouse. The epidemic was probably accelerated by the recycling of infected bovine tissues prior to the recognition of BSE. The origin of the disease itself remains unknown. The infectious agent is distinctive for the high temperatures at which it remains viable; this contributed to the spread of the disease in the United Kingdom, which had reduced the temperatures used during its rendering process. Another contributory factor was the feeding of infected protein supplements to very young calves.
This first reported case in North America was in December 1993 from Alberta, Canada., Another case reported later in May 2003. The first known U.S. occurrence came in December of the same year though it was later confirmed that it was a cow of Canadian origin and imported to the U.S. Canada announced two additional cases of BSE from Alberta in early 2005. In June 2005 Dr. John Clifford, chief veterinary officer for the United States Department of Agriculture animal health inspection service, confirmed a fully domestic case of BSE in Texas. Dr. Clifford would not identify the ranch, calling that "privileged information".
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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