A vaccine that works in newborns? Promising compound may help protect babies during vulnerable window
The underdeveloped immune systems of newborns don't respond to most vaccines, leaving them at high risk for infections like rotavirus, pertussis (whooping cough) and pneumococcus. Researchers at Boston Children's Hospital ...
Immunology Mar 04, 2013 | 5 / 5 (1) | 0 |
In a recent study, scientists have concluded that the cure rates of Miltefosine, the only oral drug for visceral leishmaniasis available, have significantly decreased. Miltefosine was introduced in the Indian subcontinent ...
Diseases, Conditions, Syndromes Mar 01, 2013 | not rated yet | 0
Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus. A new research report appearing ...
Medical research Feb 28, 2013 | not rated yet | 0 |
Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows.
Medical research Feb 27, 2013 | 5 / 5 (1) | 0
A novel tool exploits baker's yeast to expedite the development of new drugs to fight multiple tropical diseases, including malaria, schistosomiasis, and African sleeping sickness. The unique screening method uses yeasts ...
Medical research Feb 26, 2013 | not rated yet | 0
Across-the-board cuts to US R&D programs could have a devastating impact on efforts to develop new drugs for tuberculosis (TB) and HIV/AIDS, the world's first malaria vaccine, and other vital global health products in development, ...
Diseases, Conditions, Syndromes Feb 26, 2013 | not rated yet | 0
A researcher at the University of Southampton, working as part of a team from the UK and USA, believes the global eradication of malaria could be achieved by individual countries eliminating the disease within their own borders ...
Diseases, Conditions, Syndromes Feb 26, 2013 | not rated yet | 0
Many nations battling malaria face an economic dilemma: spend money indefinitely to control malaria transmission or commit additional resources to eliminate transmission completely.
Diseases, Conditions, Syndromes Feb 21, 2013 | 5 / 5 (1) | 0 |
Identifying areas of malarial infection risk depends more on daily temperature variation than on the average monthly temperatures, according to a team of researchers, who believe that their results may also apply to environmentally ...
Diseases, Conditions, Syndromes Feb 19, 2013 | not rated yet | 0
Young malaria parasites refuse to take their medicine, which may explain emerging drug resistance, new study finds
(Medical Xpress)—New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments ...
Medications Feb 19, 2013 | not rated yet | 0 |
Determined to bring relief to seizure victims, a Michigan State University research team this month begins a groundbreaking clinical drug trial that could help prevent a quarter-million African children from developing epilepsy ...
Medications Feb 16, 2013 | 5 / 5 (1) | 0
Researchers have discovered how a new class of antimalarial drugs kills the malaria parasite, showing that the drugs block a pump at the parasite surface, causing it to fill with salt.
Medical research Feb 14, 2013 | not rated yet | 0 |
An international team of tropical medicine researchers have discovered a potential method for preventing low birth weight in babies born to pregnant women who are exposed to malaria. Low birth weight is the leading cause ...
Medical research Feb 13, 2013 | not rated yet | 0
A major new centre to boost the development of drugs to tackle the foremost diseases of the developing world is to be created at the University of Dundee.
Diseases, Conditions, Syndromes Feb 13, 2013 | not rated yet | 0
Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower risk of low birth ...
Obstetrics & gynaecology Feb 12, 2013 | not rated yet | 0
Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Latest Spotlight News
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
May 20, 2013 | 4.8 / 5 (30) | 9 |
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
May 22, 2013 | 5 / 5 (4) | 6 |
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
May 24, 2013 | 4 / 5 (4) | 4 |
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
May 20, 2013 | 4.9 / 5 (7) | 5 |
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
May 23, 2013 | 4.9 / 5 (10) | 0 |
Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.
May 23, 2013 | 3 / 5 (2) | 3 |
A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...
May 23, 2013 | 4.6 / 5 (14) | 2 |
(Medical Xpress)—The human brain is able to identify individuals' voices by comparing them against an internal 'average voice' prototype, according to neuroscientists.
May 23, 2013 | 3.7 / 5 (3) | 3 |
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
May 20, 2013 | 4.8 / 5 (19) | 3 |
(Medical Xpress)—A new study by researchers in the US has shown that an ancient virus can be modified to help in the fight against the simian immunodeficiency virus SIV, which is the equivalent in monkeys ...
May 24, 2013 | 5 / 5 (3) | 0 |