Oncology & Cancer

New research opens the 'black box' of malignant melanoma

When malignant melanoma metastasizes to the brain, it is a death sentence for most patients. Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions ...

Immunology

Engineering the immune system to kill cancer cells

In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, ...

Oncology & Cancer

A combined approach to treating metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach ...

Oncology & Cancer

New treatment for advanced melanoma shows promise

In a study appearing in the April 19, 2016 issue of JAMA, Antoni Ribas, M.D., Ph.D., of the University of California-Los Angeles, and colleagues examined tumor response and overall survival following administration of the ...

Oncology & Cancer

Non-HIV-related kaposi sarcoma in BRAFi-treated patient

(HealthDay)—In a case report published online Feb. 28 in the Journal of Clinical Pharmacy and Therapeutics, researchers document non-HIV-associated Kaposi sarcoma in a male patient with myasthenia gravis and metastatic ...

Oncology & Cancer

Melanoma therapy tied to cutaneous adverse events

(HealthDay)—Anti-programmed cell death (PD)-1 therapy for metastatic melanoma is associated with the development of immune-related cutaneous events, according to research published in the March issue of the Journal of the ...

Oncology & Cancer

Nivolumab, contact immunotx treats in-transit melanoma

(HealthDay)—Nivolumab in combination with contact immunotherapy can successfully treat in-transit melanoma, according to two case reports published online Dec. 12 in the Journal of Dermatology.

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