In recent years, researchers have largely converged on the role of inflammation in the development and progression of Alzheimer's disease (AD). Studies over the past decade have revealed unexpected interactions between the ...
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. David Smith at ...
UCLA Health researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and ...
May 8, 2024
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As people age, their brains do, too. But if a brain ages prematurely, there is potential for age-related diseases such as mild cognitive impairment, dementia, or Parkinson's disease. If "brain age" could be easily calculated, ...
Apr 24, 2024
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Dedicated memory tests on smartphones enable the detection of "mild cognitive impairment," a condition that may indicate Alzheimer's disease, with high accuracy. Researchers from DZNE, the Otto-von-Guericke University Magdeburg ...
Mar 27, 2024
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A new study from researchers at the University of California, Davis, shows that a ketogenic diet significantly delays the early stages of Alzheimer's-related memory loss in mice. This early memory loss is comparable to mild ...
Mar 19, 2024
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Individuals with mild cognitive impairment, especially of the "amnestic subtype" (aMCI), are at increased risk for dementia due to Alzheimer's disease relative to cognitively healthy older adults. Now, a study co-authored ...
Feb 29, 2024
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Researchers at Weill Cornell Medicine have demonstrated how amyloid beta, a peptide associated with Alzheimer's disease, can interact with a protein receptor on immune cells in the brain. This triggers a reaction that damages ...
Nov 8, 2023
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Tai chi, the Chinese martial art that involves sequences of very slow controlled movements, may curb the symptoms and complications of Parkinson's disease for several years, reveals research published online in the Journal ...
Oct 24, 2023
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People with early Alzheimer's disease have difficulty turning when walking, according to a new study using virtual reality led by UCL researchers.
Oct 11, 2023
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Mild cognitive impairment (MCI, also known as incipient dementia, or isolated memory impairment) is a brain-function syndrome involving the onset and evolution of cognitive impairments beyond those expected based on the age and education of the individual, but which are not significant enough to interfere with their daily activities. It is often found to be a transitional stage between normal aging and dementia. Although MCI can present with a variety of symptoms, when memory loss is the predominant symptom it is termed "amnestic MCI" and is frequently seen as a prodromal stage of Alzheimer's disease. Studies suggest that these individuals tend to progress to probable Alzheimer’s disease at a rate of approximately 10% to 15% per year.
Additionally, when individuals have impairments in domains other than memory it is classified as non-amnestic single- or multiple-domain MCI and these individuals are believed to be more likely to convert to other dementias (e.g. dementia with Lewy bodies). However, some instances of MCI may simply remain stable over time or even remit. Causation of the syndrome in and of itself remains unknown, as therefore do prevention and treatment.
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