Children diagnosed with autism spectrum disorder (ASD) have greater numbers of harmful mutations in their mitochondrial DNA than family members, report Zhenglong Gu of Cornell University in Ithaca, New York, and colleagues, ...
Oct 28, 2016
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261
Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria. ...
Oct 24, 2016
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59
A mouse with dysfunctional mitochondria may hold the key to treating Leigh syndrome in humans.
Jul 18, 2016
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61
Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.
Jul 12, 2016
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Problems with insulin secretion experienced by people with Type 2 diabetes, parallel similar problems with insulin-secreting beta cells in many individuals with Down syndrome. A new study, published on May 19 in PLOS Genetics ...
May 19, 2016
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Mitochondrial dysfunction plays a critical role in the development of chemical and pharmaceutical toxicity. However, current methods to evaluate mitochondrial activity still rely on traditional tests called end-point assays, ...
Apr 4, 2016
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48
A large study by researchers with the UC Davis MIND Institute has found that a gene whose role is to suppress cellular damage from environmental stressors is nearly twice as likely to be defective in children with autism ...
Mar 31, 2016
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2
Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed for the first time in a ...
Mar 16, 2016
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7
Researchers at Schepens Eye Research Institute of Massachusetts Eye and Ear have shown a link between mitochondrial dysfunction in corneal endothelial cells and the development of Fuchs' Endothelial Corneal Dystrophy. This ...
Mar 3, 2016
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1
A team led by Massachusetts General Hospital (MGH) investigators has found that the controlled induction of the hypoxia response, the body's reaction to a reduced level of oxygen in the bloodstream, may relieve the symptoms ...
Feb 25, 2016
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