Motor Neuron Disease

Progress in the fight against ALS

A Brandeis research group has found a way to repair a vital signaling mechanism in fruit flies with symptoms of ALS. As a result, dying motor neurons regained health and the once paralyzed flies regained partial motion.

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The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body. They are generally progressive in nature, and can cause progressive disability and death. The drug riluzole can slow progression slightly; apart from this the medical care is supportive. The condition was first described in full by the French neurologist Jean-Martin Charcot in 1869.

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