Oncology & Cancer
New cancer drug to begin trials in multiple myeloma patients
Scientists at Imperial College London have developed a new cancer drug which they plan to trial in multiple myeloma patients by the end of next year.
Oct 13, 2014
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Multiple Myeloma
Oncology & Cancer
Novel compound prevents metastasis of multiple myeloma in mouse studies
In an advance against the problem of cancer metastasis, Dana-Farber Cancer Institute scientists have shown that a specially developed compound can impede multiple myeloma from spreading to the bones in mice. The findings, ...
Sep 25, 2014
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Oncology & Cancer
Inhibitor of RNA polymerase I shows promise as potential treatment for acute myeloid leukemia and multiple myeloma
The investigational drug CX-5461, which blocks the protein RNA polymerase I (Pol I), prolonged survival in mouse models of highly aggressive acute myeloid leukemia (AML) and multiple myeloma, according to data presented at ...
Sep 23, 2014
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Oncology & Cancer
New type of targeted therapy shows promise in preclinical models of B-cell malignancy
An investigational, bacterial toxin-based therapy targeted to the protein CD38, which is found on the surface of many human blood cancer cells, including multiple myeloma cells, dramatically increased survival in mice bearing ...
Sep 23, 2014
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Oncology & Cancer
New myeloma treatment options show promise
(HealthDay)—New multiple myeloma treatment options appear promising for patients aged 65 years and younger and for newly diagnosed patients who are ineligible for stem-cell transplantation, according to two studies published ...
Sep 4, 2014
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Medical research
Understanding and improving the body's fight against pathogens
Scientists from A*STAR's Bioprocessing Technology Institute (BTI) have uncovered the crucial role of two signalling molecules, DOK3 and SHP1, in the development and production of plasma cells. These discoveries, published ...
Sep 1, 2014
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Oncology & Cancer
Sensory deficits common in patients with multiple myeloma
(HealthDay)—Treatment-naive patients with multiple myeloma (MM) frequently have sensory deficits, according to a study published online Aug. 25 in the Journal of Clinical Oncology.
Aug 28, 2014
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Oncology & Cancer
Promising new cancer therapy uses molecular 'Trash Man' to exploit a common cancer defense
While many scientists are trying to prevent the onset of a cancer defense mechanism known as autophagy, researchers at Virginia Commonwealth University Massey Cancer Center are leveraging it in a new therapy that causes the ...
Aug 27, 2014
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Oncology & Cancer
Researchers use calcium isotope analysis to predict myeloma progression
A team of researchers from Arizona State University and Mayo Clinic is showing how a staple of Earth science research can be used in biomedical settings to predict the course of disease.
Aug 12, 2014
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Oncology & Cancer
Engineered measles vaccine wipes out woman's cancer
A potent dose of engineered measles virus has been shown for the first time to have completely wiped out a woman's cancer, US scientists reported this week.
May 15, 2014
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