Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called "circadian clock" are complex, and the molecular processes behind it have ...
5 / 5 (2) |
0
|
Royalty Pharma has let its latest takeover bid for Irish drugmaker Elan lapse as it decided against pressing ahead with a court challenge of a requirement that it withdraw the offer.
not rated yet |
0
For less than $100, University of Washington researchers have designed a computer-interfaced drawing pad that helps scientists see inside the brains of children with learning disabilities while they read ...
5 / 5 (2) |
0
Shareholders of Irish drugmaker Elan Corp. PLC have potentially ended a takeover bid from Royalty Pharma by voting in favor of an Elan share buyback plan.
not rated yet |
0
Shares of Elan Corp PLC jumped Friday after the Irish drugmaker said it will explore a possible sale of the company while its board continues to fend off a hostile takeover bid from Royalty Pharma.
not rated yet |
0
(Medical Xpress)—Basal cell carcinoma is the most common form of cancer. While unlikely to metastasize and therefore associated with low mortality, it can be disfiguring and costly to treat. Typically, ...
5 / 5 (2) |
0
|
(Medical Xpress)—A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, ...
5 / 5 (2) |
0
|
Researchers at the University of British Columbia have developed a new magnetic resonance imaging (MRI) technique that detects the telltale signs of multiple sclerosis in finer detail than ever before – ...
5 / 5 (2) |
0
|
(Medical Xpress)—Dr. Anita Koshy sees a common and typically harmless brain parasite as a potential key to unlocking secrets of neurobiology that can be used to intervene in diseases such as Alzheimer's and multiple sclerosis.
5 / 5 (1) |
0
(Medical Xpress)—A new Cochrane review led by King's College London has found that providing home palliative care doubles the odds that someone with a terminal illness can die at home if they want to, and ...
not rated yet |
0
A new study shows that common mutant forms of the deadly JC polyomavirus are not responsible for the pathogen's main attack, which causes a brain-damaging disease in immunocompromised patients called progressive ...
not rated yet |
0
Irish biotechnology company Elan rejected on Monday the latest takeover bid from US group Royalty Pharma worth about $7.9 billion (6.0 billion euros).
not rated yet |
0
A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death. This ...
5 / 5 (2) |
0
Shares of Elan Corp. PLC jumped Friday after Royalty Pharma once again raised its offer to buy the Irish drugmaker in an increasingly bitter takeover fight.
not rated yet |
0
A phase 1 clinical trial for the first treatment to reset the immune system of multiple sclerosis (MS) patients showed the therapy was safe and dramatically reduced patients' immune systems' reactivity to myelin by 50 to ...
5 / 5 (8) |
0
|
Multiple sclerosis (abbreviated to MS, known as disseminated sclerosis or encephalomyelitis disseminata) is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms. Disease onset usually occurs in young adults, and it is more common in women. It has a prevalence that ranges between 2 and 150 per 100,000. MS was first described in 1868 by Jean-Martin Charcot.
MS affects the ability of nerve cells in the brain and spinal cord to communicate with each other effectively. Nerve cells communicate by sending electrical signals called action potentials down long fibers called axons, which are contained within an insulating substance called myelin. In MS, the body's own immune system attacks and damages the myelin. When myelin is lost, the axons can no longer effectively conduct signals. The name multiple sclerosis refers to scars (scleroses—better known as plaques or lesions) particularly in the white matter of the brain and spinal cord, which is mainly composed of myelin. Although much is known about the mechanisms involved in the disease process, the cause remains unknown. Theories include genetics or infections. Different environmental risk factors have also been found.
Almost any neurological symptom can appear with the disease, and often progresses to physical and cognitive disability. MS takes several forms, with new symptoms occurring either in discrete attacks (relapsing forms) or slowly accumulating over time (progressive forms). Between attacks, symptoms may go away completely, but permanent neurological problems often occur, especially as the disease advances.
There is no known cure for multiple sclerosis. Treatments attempt to return function after an attack, prevent new attacks, and prevent disability. MS medications can have adverse effects or be poorly tolerated, and many patients pursue alternative treatments, despite the lack of supporting scientific study. The prognosis is difficult to predict; it depends on the subtype of the disease, the individual patient's disease characteristics, the initial symptoms and the degree of disability the person experiences as time advances. Life expectancy of people with MS is 5 to 10 years lower than that of the unaffected population.
This text uses material from Wikipedia licensed under CC BY-SA
Validating maps of the brain's resting state
Kick back and shut your eyes. Now stop thinking. You have just put your brain into what neuroscientists call its resting state. What the brain is doing when an individual is not focused on the outside world ...
Scientists create way to see structures that store memories in living brain
Oscar Wilde called memory "the diary that we all carry about with us." Now a team of scientists has developed a way to see where and how that diary is written.
Wireless subretinal prostheses allows blind mice to see light
(Medical Xpress)—A team of researchers from the U.S. and Scotland has developed a new type of retinal prostheses designed to restore sight to blind patients. In their paper published in the journal Nature Co ...
Diapocynin, a synthetic molecule derived from a naturally occurring compound (apocynin), has been found to protect neurobehavioral function in mice with Parkinson's Disease symptoms by preventing deficits in motor coordination.
Distracted walking: Injuries soar for pedestrians on phones
More than 1,500 pedestrians were estimated to be treated in emergency rooms in 2010 for injuries related to using a cell phone while walking, according to a new nationwide study.
Researchers pinpoint how smoking causes osteoporosis
(Medical Xpress)—Human bone breaks down and regenerates naturally all the time, in a perfectly balanced dance that maintains skeletal integrity.
Laughing gas does not increase heart attacks
(Medical Xpress)—Nitrous oxide—best known as laughing gas—is one of the world's oldest and most widely used anesthetics. Despite its popularity, however, experts have questioned its impact on the risk ...
Model recreates wear and tear of osteoarthritis
(Medical Xpress)—There's a reason osteoarthritis is often called wear-and-tear arthritis: Repeated stress on joints over time results in degeneration of the soft cartilage that normally distributes loads ...
Study of vocal impersonations reveals how we manipulate our voices
A study of vocal impersonations has shown for the first time how speech production and voice perception systems in the brain interact to influence the way our voices sound. The research, supported by the ...
Women say they place a priority on a potential partner's earning prospects, and men claim to value a potential partner's physical attractiveness; these sex differences have been widely studied by psychologists for decades.
