Oncology & Cancer
Dogs join fight against bone cancer
(HealthDay)—Man's best friend will be part of an effort to find better treatments for a type of bone cancer in children and young adults, researchers report.
May 15, 2014
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Osteosarcoma
Oncology & Cancer
Tumor suppressor gene TP53 mutated in 90 percent of most common childhood bone tumor
The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role ...
Apr 3, 2014
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Oncology & Cancer
Researchers say gold-based drug shows promise for fighting bone cancer in people and pets
(Medical Xpress)—A gold-based drug currently used in human and veterinary medicine to manage certain immune diseases may prove useful in combating osteosarcoma, a devastating bone cancer that affects both dogs and people, ...
Mar 26, 2014
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Oncology & Cancer
Genetic variant may identify pediatric osteosarcoma patients at risk for metastasis
A genomewide association study (GWAS) has revealed two specific variations in the NFIB gene that may identify which children and adolescents with osteosarcoma have metastatic disease or are at high risk for metastasis, according ...
Nov 5, 2013
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Oncology & Cancer
Combining Chinese and Western medicine could lead to new cancer treatments
Combining traditional forms of Chinese and Western medicine could offer new hope for developing new treatments for liver, lung, colorectal cancers and osteosarcoma of the bones.
Sep 28, 2013
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Oncology & Cancer
Pathways activated in most K9 bone tumors not driving the worst bone tumors
Many cancers show inappropriate activation of a cell signaling pathway called NOTCH. In the developing body, NOTCH tells brain cells to grow and proliferate. It should be quiet in the adult body, but cancers restart NOTCH ...
Jul 23, 2013
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Oncology & Cancer
Study finds missing piece of pediatric cancer puzzle
Most of the time, it takes decades of accumulating genetic errors for a tumor to develop. While this explains the general occurrence of cancer in adults, it leaves a gap in understanding of the cause of pediatric tumors.
Jul 19, 2013
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Oncology & Cancer
Team creates realistic 3-D tumour through tissue engineering using silk scaffolds
A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track ...
Jun 20, 2013
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Oncology & Cancer
Lexatumumab tolerated for pediatric solid tumors
(HealthDay)—Lexatumumab, an agonistic, full human monoclonal antibody against tumor necrosis factor-related apoptosis-inducing ligand receptor 2, is well tolerated and may lessen certain clinical symptoms in some pediatric ...
Oct 16, 2012
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Surgery
Novel surgery removes rare tumor, rebuilds face and jaw
Using a novel surgical approach, it's possible to rebuild a functional lower jaw and mouth, and preserve a patient's ability to eat and speak after removing an invasive facial tumor, according to a new report from Henry Ford ...
Sep 7, 2012
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