Neuroscience

Abnormal neuron activity manifests as parental neglect

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child ...

Neuroscience

Speeding up drug discovery for brain diseases

A research team led by Whitehead Institute scientists has identified 30 distinct chemical compounds—20 of which are drugs undergoing clinical trial or have already been approved by the FDA—that boost the protein production ...

Medical research

Treating core Rett syndrome symptoms

A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents.

Neuroscience

Research provides important insight on the brain-body connection

A study conducted by University of Arkansas researchers reveals that neurons in the motor cortex of the brain exhibit an unexpected division of labor, a finding that could help scientists understand how the brain controls ...

Neuroscience

A new drug shows preclinical efficacy in Rett syndrome

A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett syndrome in preclinical models. The study was led by Dr. Manel Esteller, ...

Neuroscience

Researchers reverse symptoms in neurologic disease model

It is a parent's nightmare: a child is born apparently healthy, then stops meeting developmental milestones at one year old. Her verbal and motor skills vanish, and irregular breathing, seizures, and a host of other problems ...

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