Systemic Sclerosis
Genes reveal which patients will benefit from scleroderma drug
Systemic sclerosis, also known as scleroderma, is a rare autoimmune connective tissue disorder that's difficult to treat. However, thanks to new research at Northwestern University Feinberg School of Medicine and Dartmouth's ...
Diseases, Conditions, Syndromes
Apr 10, 2013 |
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AAD: Skin changes can be first sign of underlying condition
(HealthDay)—Skin changes, including new rash, new growths, discoloration, and changes in texture, could be among the first signs indicating an underlying medical condition, according to information presented ...
Diseases, Conditions, Syndromes
Mar 01, 2013 |
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Discovery shows medications can treat inflammation without increasing risk for infection
In a discovery that can fundamentally change how drugs for arthritis, and potentially many other diseases, are made, University of Utah medical researchers have identified a way to treat inflammation while potentially minimizing ...
Inflammatory disorders
Nov 11, 2012 |
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Subclinical atherosclerosis noted in diffuse scleroderma
(HealthDay)—Patients with diffuse systemic sclerosis (SSc), without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online ...
Arthritis & Rheumatism
Aug 29, 2012 |
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Haematopoietic stem cell transplantation increases survival in systemic sclerosis patients
Initial results from an international, investigator-initiated, open label phase III trial were presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism. Data indicate that haematopoietic stem ...
Arthritis & Rheumatism
Jun 07, 2012 |
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Scientists identify agent that can block fibrosis of skin, lungs
Researchers at the University of Pittsburgh School of Medicine have identified an agent that in lab tests protected the skin and lungs from fibrosis, a process that can ultimately end in organ failure and even death because ...
Medical research
May 30, 2012 |
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Systemic sclerosis complications more severe in African Americans than Caucasians
African Americans have more severe complications from systemic sclerosis, also known as scleroderma, than Caucasians. Findings published today in, Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), ...
Arthritis & Rheumatism
May 10, 2012 |
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Mechanism ID'd for benefit of stem cells in autoimmunity
(HealthDay) -- Bone marrow mesenchymal stem cells (BMMSCs) activate a mechanism involving coupling of FAS/FAS ligand to induce T cell apoptosis and immune tolerance, according to an experimental study published ...
Medical research
May 02, 2012 |
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New genetic path for scleroderma: Patient biopsies reveal potential new target for therapy
A genetic pathway previously known for its role in embryonic development and cancer has been identified as a target for systemic sclerosis, or scleroderma, therapy. The finding, discovered by a cross-disciplinary team led ...
Arthritis & Rheumatism
Mar 19, 2012 |
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Northwestern to explore personalized medicine for scleroderma
Northwestern Medicine researchers have received two five-year grants totaling $953,000 from the National Institutes of Health's (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases to study scleroderma, ...
Diseases, Conditions, Syndromes
Dec 02, 2011 |
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Scleroderma study identifies roadblocks to employment
Systemic scleroderma has slowed Tracy Zinn but it has not stopped her from working. Thanks in part to determination and an accommodating employer, Zinn is now in her 13th year as an account executive for a ...
Diseases, Conditions, Syndromes
Jul 12, 2011 |
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Study suggests systemic sclerosis is an independent risk factor for atherosclerosis
A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis. Conventional cardiovascular risk factors such as age ...
Diseases, Conditions, Syndromes
May 10, 2011 |
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Systemic sclerosis or systemic scleroderma is a systemic autoimmune disease or systemic connective tissue disease that is a subtype of scleroderma. It is characterized by deposition of collagen in the skin and, less commonly, in the kidneys, heart, lungs & stomach. Female to male ratio is 4:1. The peak age of onset is between 30-50 years.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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