Cancer Cell

Scientists discover key process that allows colon cancer to metastasize

A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability ...

Cancer created Nov 12, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Study sheds light on how pancreatic cancer begins

A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages.

Cancer created Nov 29, 2012 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Mitochondrial metabolic regulator SIRT4 guards against DNA damage

(Medical Xpress)—Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.

Cancer created Apr 05, 2013 | popularity 5 / 5 (4) | comments 2 | with audio podcast

Team finds gene that promotes drug resistance in cancer

Scientists from the University of Iowa and Brigham Young University (BYU) have identified a gene that may be a target for overcoming drug resistance in cancer. The finding could not only improve prognostic and diagnostic ...

Cancer created Jan 14, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Scientists discover new way to target cancer

Scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth.

Cancer created Dec 12, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers discover a new therapy that prevents lung cancer growth in mice

Lung cancer is one of the most aggressive types of cancer and the most common cause of death from this disease worldwide. Despite the progress in the molecular biology of lung cancer achieved in recent years, the mechanisms ...

Cancer created Aug 13, 2012 | popularity 5 / 5 (3) | comments 0

BRAF inhibitor treatment causes melanoma cells to shift how they produce energy

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...

Cancer created Mar 08, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers discover master regulator that drives majority of lymphoma

A soon-to-be-tested class of drug inhibitors were predicted to help a limited number of patients with B-cell lymphomas with mutations affecting the EZH2 protein. However, a research team, led by investigators at Weill Cornell ...

Cancer created May 13, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Gene inactivation drives spread of melanoma: study

Why do some cancers spread rapidly to other organs and others don't metastasize? A team of UNC researchers led by Norman Sharpless, MD, have identified a key genetic switch that determines whether melanoma, a lethal skin ...

Cancer created Jun 11, 2012 | popularity 3 / 5 (4) | comments 0 | with audio podcast

Study reveals origins of esophageal cancer

(Medical Xpress) -- Researchers at Columbia University Medical Center (CUMC) have identified the critical early cellular and molecular events that give rise to a type of esophageal cancer called esophageal ...

Cancer created Jan 17, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists break through pancreas cancer treatment barrier

Pancreas cancer tumors spread quickly and are notoriously resistant to treatment, making them among the deadliest of malignancies. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor ...

Cancer created Mar 19, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Protein that helps tumor blood vessels mature could make cancer drugs more effective

Since anti-cancer drugs are carried to tumors by the bloodstream, abnormal blood vessel development can hamper delivery. In a paper published Aug. 14 in Cancer Cell, researchers at Sanford-Burnham Medica ...

Cancer created Aug 13, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Mice at risk of asthma, allergies can fight off skin cancer

A molecule involved in asthma and allergies has now been shown to make mice resistant to skin cancer, according to scientists at Washington University School of Medicine in St. Louis.

Cancer created Oct 15, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Study shows how chronic inflammation can cause cancer

A hormone-like substance produced by the body to promote inflammation can cause an aggressive form of leukemia when present at high levels, according to a new study by researchers at the Ohio State University Comprehensive ...

Cancer created Nov 12, 2012 | popularity 5 / 5 (2) | comments 0

Scientists reveal aggressive breast cancer's metastatic path

Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...

Cancer created Jan 14, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast