Metaplasia is defined as the replacement of a fully differentiated cell type by another. There are several classical examples of metaplasia, one of the most frequent is called Barrett's esophagus. Barrett's esophagus is characterized ...
Apr 21, 2021
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Researchers from the group of Hans Clevers (Hubrecht Institute) developed the first patient-derived organoid model for cervical cancer. They also modeled the healthy human cervix using organoids. In close collaboration with ...
Apr 13, 2021
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In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi, Ph.D., demonstrates that neural stem cells—the stem cells of the nervous system—age rapidly.
Apr 12, 2021
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Institute of Molecular Biotechnology of the Austrian Academy of Sciences have demonstrated that different viruses can lead to brain malformations through diverse mechanisms by using human brain organoid models. The results ...
Apr 9, 2021
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In all adult vertebrates, neural stem cells can be recruited to produce new neurons in the brain. However, little is known about these so-called 'activation' processes.
Apr 8, 2021
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The Yasuhiro Takashima lab shows that naïve iPS cells can be induced to form all the stages that mimic early placenta development in humans.
Apr 8, 2021
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Age-related macular degeneration (AMD), which leads to a loss of central vision, is the most frequent cause of blindness in adults 50 years of age or older, affecting an estimated 196 million people worldwide. There is no ...
Mar 29, 2021
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Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. HSCs can either duplicate to produce more stem ...
Mar 25, 2021
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Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in ...
Mar 16, 2021
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Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, ...
Mar 5, 2021
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