Cell Stem Cell

Stem-cell-based strategy boosts immune system in mice

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...

Immunology created May 16, 2013 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Human brain cells developed in lab, grow in mice

A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat ...

Medical research created May 08, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Gene thought to make heart tissues turns out to make blood and muscles as well

New research out of the Lillehei Heart Institute at the University of Minnesota shows that by turning on just a single gene, Mesp1, different cell types including the heart, blood and muscle can be created from stem cells.

Genetics created May 02, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Turning human stem cells into brain cells sheds light on neural development

Medical researchers have manipulated human stem cells into producing types of brain cells known to play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia and autism. The new model cell system ...

Medical research created May 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Brain development is guided by 'junk' DNA that isn't really junk

(Medical Xpress)—Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

Genetics created Apr 15, 2013 | popularity 4.9 / 5 (14) | comments 2 | with audio podcast

Reinventing drug discovery: Promising drug target for ALS

Using a new stem-cell based drug screening technology with the potential to reinvent and greatly reduce the cost of the way new pharmaceuticals are developed, Harvard Stem Cell Institute (HSCI) researchers ...

Diseases, Conditions, Syndromes created Apr 18, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists turn skin cells into brain cells

Scientists at the Gladstone Institutes have for the first time transformed skin cells—with a single genetic factor—into cells that develop on their own into an interconnected, functional network of brain cells. ...

Medical research created Jun 07, 2012 | popularity 5 / 5 (6) | comments 3 | with audio podcast

Extra chromosome 21 removed from Down syndrome cell line

(Medical Xpress)—University of Washington scientists have succeeded in removing the extra copy of chromosome 21 in cell cultures derived from a person with Down syndrome, a condition in which the body's ...

Medical research created Nov 09, 2012 | popularity 4.9 / 5 (11) | comments 0 | with audio podcast

Cells forged from human skin show promise in treating multiple sclerosis, myelin disorders

A study out today in the journal Cell Stem Cell shows that human brain cells created by reprogramming skin cells are highly effective in treating myelin disorders, a family of diseases that includes multiple sclerosis and ra ...

Medical research created Feb 07, 2013 | popularity not rated yet | comments 2 | with audio podcast

Ills of aging blood: Short-circuited stem cell programming linked to failing blood development

As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune ...

Medical research created Feb 15, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Scientists use an old theory to discover new targets in the fight against breast cancer

Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have ...

Cancer created Feb 07, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Using human brain cells to make mice smarter

Glial cells – a family of cells found in the human central nervous system and, until recently, considered mere "housekeepers" – now appear to be essential to the unique complexity of the human brain. Scientists reached ...

Medical research created Mar 07, 2013 | popularity 3.7 / 5 (3) | comments 2 | with audio podcast

Researchers connect new genetic signature to leukemia

(Medical Xpress)—University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cell, and then to use the new genetic signature to identify ...

Cancer created Aug 27, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Revolutionary techniques could help harness patients' own immune cells to fight disease

The human body contains immune cells programmed to fight cancer and viral infections, but they often have short lifespans and are not numerous enough to overcome attacks by particularly aggressive malignancies ...

Medical research created Jan 03, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Drug targets hard-to-reach leukemia stem cells responsible for relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms ...

Cancer created Jan 17, 2013 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast