Cell Stem Cell

Genetics

How glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. Glial cells have long been regarded primarily as supportive cells, but researchers increasingly recognize that they play an active role in the communication ...

Diseases, Conditions, Syndromes

Lab model offers hope for macular degeneration patients

Age-related macular degeneration (AMD), which leads to a loss of central vision, is the most frequent cause of blindness in adults 50 years of age or older, affecting an estimated 196 million people worldwide. There is no ...

Oncology & Cancer

CAR-T immunotherapies may have a new player

Emerging CAR-T immunotherapies leverage modified versions of patient's T-cells to target and kill cancer cells. In a new study, published June 28 online in Cell Stem Cell, researchers at University of California San Diego ...

Diseases, Conditions, Syndromes

Zika virus may cause microcephaly by hijacking human immune molecule

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known ...

Medical research

Esophageal cancer: Discovery of the mechanisms involved

Metaplasia is defined as the replacement of a fully differentiated cell type by another. There are several classical examples of metaplasia, one of the most frequent is called Barrett's esophagus. Barrett's esophagus is characterized ...

Oncology & Cancer

Making better, ready-made CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells from a patient's own blood are engineered to carry so-called chimeric antigen receptors (CAR) that enhance the T cells' ability to attack and kill tumor cells. While CAR-T therapy is a ...

Oncology & Cancer

New findings explain how UV rays trigger skin cancer

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the U.S. in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from ...

Medical research

Two studies shed light on how, where body can add new fat cells

Gaining more fat cells is probably not what most people want, although that might be exactly what they need to fight off diabetes and other diseases. How and where the body can add fat cells has remained a mystery—but two ...

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