Cell

Immunology

How one inflammatory disorder exacerbates another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...

Diseases, Conditions, Syndromes

Predicting long COVID at initial point of COVID-19 diagnosis

A significant portion of people who contract the SARS-CoV-2 virus—some estimates suggest more than 40 percent—suffer chronic effects known as Post Acute Sequelae of COVID-19 (PASC), commonly referred to as long COVID. ...

Neuroscience

An open-source miniature brain microscope

"Our dream was to invent a window into the brain, so we could see what happens inside when we're thinking, planning, feeling, and remembering," says Professor May-Britt Moser, describing conversations she and her long-term ...

Medical research

Role of lymphatic system in bone healing revealed

It was previously assumed that bones lacked lymphatic vessels, but new research from the MRC Human Immunology Unit at Oxford's MRC Weatherall Institute for Molecular Medicine not only locates them within bone tissue, but ...

Diseases, Conditions, Syndromes

CAR T cell therapy could reach beyond cancer

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small ...

Diseases, Conditions, Syndromes

What makes an mRNA vaccine so effective against severe COVID-19?

The first two vaccines created with mRNA vaccine technology—the Pfizer/BioNTech and Moderna COVID-19 vaccines—are arguably two of the most effective COVID vaccines developed to date. In clinical trials, both were more ...

Oncology & Cancer

New insights into melanoma brain metastases

Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma. Although new immunotherapies are effective in some patients with melanoma brain metastases, ...

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