Developmental Cell
Growing new arteries, bypassing blocked ones
Scientific collaborators from Yale School of Medicine and University College London (UCL) have uncovered the molecular pathway by which new arteries may form after heart attacks, strokes and other acute illnesses bypassing ...
Medical research
Apr 29, 2013 |
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Study uncovers molecular role of gene linked to blood vessel formation
University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.
Medical research
Apr 29, 2013 |
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Double drug combo could shut down abnormal blood vessel growth that feeds disease
A new study by researchers at Weill Cornell Medical College shows combining two already-FDA approved drugs may offer a new and potent punch against diseases in which blood vessel growth is abnormal—such as cancer, diabetic ...
Medical research
Sep 10, 2012 |
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Researchers find possible genetic clues to organ development, birth defects (w/ Video)
(Medical Xpress)—Using cutting-edge time-lapse photography, University of Southern California (USC) researchers have discovered clues to the development of the head at the cellular level, which could point scientists to ...
Medical research
Feb 11, 2013 |
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Wnt signaling pathway plays key role in adult nerve cell generation: study
Researchers from the University of Utah have gained new insight into the regulation of adult nerve cell generation in the hypothalamus, the part of the brain that regulates many aspects of behavior, mood, and metabolism. ...
Medical research
Sep 10, 2012 |
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Cilia guide neuronal migration in developing brain
A new study demonstrates the dynamic role cilia play in guiding the migration of neurons in the embryonic brain. Cilia are tiny hair-like structures on the surfaces of cells, but here they are acting more ...
Medical research
Nov 12, 2012 |
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Scientists discover key pathway for development of insulin-producing cells
(Medical Xpress) -- Researchers at the Stanford University School of Medicine have identified a molecular signaling pathway that drives the growth and maturation of young human beta cells — the insulin-producing cell ...
Medical research
Jul 17, 2012 |
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Using planarian flatworms to understand organ regeneration
Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.
Medical research
Oct 25, 2012 |
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Clues found to way embryonic kidney maintains its fleeting stem cells
Studying mice and humans, researchers at Washington University School of Medicine in St. Louis and their collaborators in Paris have identified two proteins that are required to maintain a supply of stem cells ...
Medical research
Jun 11, 2012 |
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Novel microscale epigenomics technology: Possible to study the epigenome of rare cell populations and biopsy samples
Scientists at A*STAR's Genome Institute of Singapore (GIS) have successfully developed a method to map the epigenome using 100 times fewer cells than was previously possible. The discovery, published in the journal Developmental Ce ...
Genetics
Feb 11, 2013 |
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Not all fat is packaged the same way, researchers find
Fat is stored in the body in two distinct ways, Yale researchers have discovered. While the finding may not help people shed excess pounds, it may shed light on how to prevent health problems associated with ...
Overweight and Obesity
Feb 15, 2013 |
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Study uncovers mechanism by which tumor suppressor MIG6 triggers cell suicide
Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells—a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. ...
Cancer
Sep 24, 2012 |
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Tweaking gene expression to repair lungs
A healthy lung has some capacity to regenerate itself like the liver. In COPD, these reparative mechanisms fail. HDAC therapies may be useful for COPD, as well as other airway diseases. The levels of HDAC2 ...
Medical research
Feb 25, 2013 |
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Gene 'switch' may explain DiGeorge syndrome severity
The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.
Genetics
Aug 23, 2012 |
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Study adds to efforts to find more effective anti-inflammatory drugs
Researchers have discovered a previously unknown function for a protein that could add to the expanding arsenal of potential new drugs for battling inflammation and tissue fibrosis in a number of disease processes.
Inflammatory disorders
Sep 27, 2012 |
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