EMBO Journal

Medical research

The absence of a single protein spurs muscle aging in mice

IRB Barcelona researchers discover that the loss of the protein Mitofusin 2 in the muscles of young mice speeds up aging and causes early sarcopenia, thus leading to the muscle quality of aged mice.Sarcopenia, which is muscle ...

Neuroscience

Revealing roles of dementia proteins in normal memory

New research has revealed how the tau protein, a critical element in the formation of Alzheimer's disease, is also involved in normal learning processes in the healthy brain—potentially providing a focal point for future ...

Medical research

A closer look at brain organoid development

How close to reality are brain organoids, and which molecular mechanisms underlie the remarkable self-organizing capacities of tissues? Researchers already have succeeded in growing so-called "cerebral organoids" in a dish ...

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

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