Molecular Cancer Research

Oncology & Cancer

Protein loss promotes cell migration

The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. It can be oncogenic or tumor suppressive, depending on the cancer, but its role in colorectal cancer has not been established.

Oncology & Cancer

'Christmas berry' plant compound could fight Uveal melanoma

Doctors diagnose about 2000 adults with uveal melanoma, a cancer of the eye, every year. In half of cases, the disease metastasizes to the liver. For these patients treatment options are scarce. Researchers at the Sidney ...

Oncology & Cancer

Fat cells may inactivate chemotherapeutic drug

Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.

Oncology & Cancer

New target found to attack an incurable brain tumor in children

A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic ...

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