Molecular Cell

Team uncovers new insight into cell development and cancer

Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute ...

Cancer created Dec 27, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Methylome modifications offer new measure of our 'biological' age

Women live longer than men. Individuals can appear or feel years younger – or older – than their chronological age. Diseases can affect our aging process. When it comes to biology, our clocks clearly tick differently.

Medical research created Nov 21, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Binding sites for LIN28 protein found in thousands of human genes

A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which ...

Genetics created Sep 04, 2012 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Researchers reveal crucial immune fighter role of the STING protein

Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.

Medical research created Jun 18, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Cancer-promoting protein found to also suppress cell growth

Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...

Medical research created Mar 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Why cells stick: Phenomenon extends longevity of bonds between cells

Research carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures, an essential function ...

Medical research created Feb 14, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists link excess sugar to cancer

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also ...

Medical research created Feb 01, 2013 | popularity 4.7 / 5 (19) | comments 12 | with audio podcast

Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports

(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...

Cancer created Dec 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Insight into DNA reprogramming during egg and sperm cell development

Scientists at the Babraham Institute have gained a new understanding of when and how the DNA in developing egg and sperm cells is 'reset', in preparation for making a new embryo. It is well known that small chemical groups ...

Genetics created Dec 06, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers ID gene that turns carbs into fat: Discovery could help development of treatment for fatty liver, diabetes

A gene that helps the body convert that big plate of holiday cookies you just polished off into fat could provide a new target for potential treatments for fatty liver disease, diabetes and obesity.

Genetics created Dec 06, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Scientists create roadmap to metabolic reprogramming for aging

In efforts to understand what influences life span, cancer and aging, scientists are building roadmaps to navigate and learn about cells at the molecular level.

Medical research created Nov 29, 2012 | popularity 5 / 5 (8) | comments 0 | with audio podcast

Metabolic protein launches sugar feast that nurtures brain tumors

Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which ...

Cancer created Nov 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

New developments reveal a molecule with a promising function in terms of cancer treatment.

Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...

Cancer created Oct 30, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Target for obesity drugs comes into focus

(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

Medical research created Oct 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Cell death discovery suggests new ways to protect female fertility

Melbourne researchers have identified a new way of protecting female fertility, offering hope to women whose fertility may be compromised by the side-effects of cancer therapy or by premature menopause.

Medical research created Sep 22, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast