Tyrosine kinase inhibitors (TKIs) kill cancerous cells by inducing programmed cell death. They are of enormous therapeutic benefit to patients with chronic myeloid leukemia (CML) and certain types of lung ...
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(Medical Xpress) -- Researchers working for German pharmaceutical company Immatics Biotechnologies GmbH, have outlined two successful outcomes for their multipeptide vaccine IMA901 in a paper they’ve had published in ...
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Neural precursor cells (NPC) in the young brain suppress certain brain tumors such as high-grade gliomas, especially glioblastoma (GBM), which are among the most common and most aggressive tumors. Now researchers of the Max ...
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A melanoma is a malignant form of skin cancer and is one of the most aggressive types of tumors there is. Treatment is particularly difficult, because melanomas are usually resistant against conventional chemotherapy ...
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(Medical Xpress) -- Researchers working in Australia have found that certain breast cancer cells are able to switch off the gene that is responsible for causing the production of interferon, an immunity response protein that ...
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(Medical Xpress) -- Back in February, a team of researchers led by Jonathan Tilly published a paper in Nature Medicine describing new work that they said backed up research done in 2004 (resulting in a paper published in the ...
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The biological mechanism of sunburn – the reddish, painful, protective immune response from ultraviolet (UV) radiation – is a consequence of RNA damage to skin cells, report researchers at the University ...
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Researchers from Brigham and Women's Hospital (BWH) have made a groundbreaking discovery that will shape the future of melanoma therapy. The team, led by Thomas S. Kupper, MD, chair of the BWH Department of Dermatology, and ...
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New research in Nature Medicine shows that boosting a protein pathway in the body's blood making system protects mice from otherwise fatal radiation poisoning.
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(Medical Xpress) -- With the University of Pittsburgh's development of a cell-free, biodegradable artery graft comes a potentially transformative change in coronary artery bypass surgeries: Within 90 days after surgery, the ...
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(Medical Xpress) -- In people and most animals, the nerves that carry electrical signals from one part of the body to another must have a protective coating (called a myelin sheath) to allow signals to travel properly. When ...
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A study led by Vanderbilt-Ingram Cancer Center (VICC) investigators has identified a gene expression pattern that may explain why chemotherapy prior to surgery isn't effective against some tumors and suggests new therapy ...
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(Medical Xpress) -- Endometriosis, which can cause severe pain and even infertility in the estimated 8.5 million U.S. women it affects, is driven by one of the cell's master regulators steroid receptor coactivator ...
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While vaccines are perhaps medicine's most important success story, there is always room for improvement. Researchers at Oregon Health & Science University's Oregon National Primate Research Center (ONPRC) appear to have ...
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Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called ...
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