Nucleic Acids Research

Nucleic Acids Research is a peer-reviewed scientific journal published by Oxford University Press. It covers research on nucleic acids, such as DNA and RNA, and related work. Some of its content is available under an open access license. According to the Journal Citation Reports, the journal s 2010 impact factor is 7.836. The journal publishes two yearly special issues, one dedicated to biological databases, published in January since 1993 and the other on biological web servers, published in July since 2003.


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Computer program identifies rare mutations harbored within diverse populations of cancer cells and microorganisms

A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant ...

Cancer created Apr 24, 2013 | popularity not rated yet | comments 0

Study identifies 'chink in the armor' of Schmallenberg virus

A key building block in the Schmallenberg virus could be targeted by anti-viral drugs, according to a new study led from the University of Leeds.

Medical research created Apr 17, 2013 | popularity not rated yet | comments 0 | with audio podcast

LoFreq: Ultrafast detection of microbe and cancer cell mutations

Scientists at A*STAR's Genome Institute of Singapore (GIS) have developed a novel technique to precisely monitor and study the evolution of micro-organisms such as viruses and bacteria. This is an extremely important capability ...

Medical research created Mar 07, 2013 | popularity not rated yet | comments 0

Protein that represses critical checkpoint protein for cellular growth helps drive tumor development

(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth ...

Cancer created Feb 13, 2013 | popularity not rated yet | comments 0

Novel gene-searching software improves accuracy in disease studies

A novel software tool, developed at The Children's Hospital of Philadelphia, streamlines the detection of disease-causing genetic changes through more sensitive detection methods and by automatically correcting for variations ...

Genetics created Jan 22, 2013 | popularity not rated yet | comments 0

Novel technique reveals dynamics of telomere DNA structure

Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural ...

Medical research created Jan 17, 2013 | popularity 5 / 5 (2) | comments 0

Researchers use supercomputer simulations to understand how some carcinogens evade removal

A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette ...

Cancer created Nov 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

Creutzfeldt-Jakob, 'Mad Cow' blood test now on the horizon

(Medical Xpress)—A simple blood test for Creutzfeldt-Jakob Disease and Mad Cow disease is a step closer, following a breakthrough by medical researchers at the University of Melbourne.

Diseases, Conditions, Syndromes created Sep 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Link between prostate cancer and vitamin A may lead to improved treatment

(Medical Xpress)—Cancer scientists at the University of York have shown a link between prostate cancer and vitamin A for the first time.

Cancer created Sep 05, 2012 | popularity 5 / 5 (1) | comments 0

Hepatitis C 'switch' offers target for new drug research

Scientists have discovered a 'switch' in the Hepatitis C virus which could be used as a target for new kinds of drug treatment.

Diseases, Conditions, Syndromes created May 31, 2012 | popularity not rated yet | comments 0

Cancer epigenetics: Breakthrough in ID'ing target genes

Cancer is usually attributed to faulty genes, but growing evidence from the field of cancer epigenetics indicates a key role for the gene "silencing" proteins that stably turn genes off inside the cell nucleus. ...

Cancer created Mar 13, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Map reveals cancer hotspots

(Medical Xpress) -- A new technique is helping researchers to pinpoint genetic information that contributes to cancer development.

Cancer created Feb 22, 2012 | popularity 5 / 5 (1) | comments 0