Nucleic Acids Research

Diseases, Conditions, Syndromes

Discovering the secrets of viral sequences in COVID-19

Since the beginning of 2020, labs from all around the world have been sequencing the material from positive tests of people affected by COVID-19 and then depositing sequences mostly to three points of collection: GenBank, ...

Medical research

RNA structures of coronavirus reveal potential drug targets

The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University. The RNA structures ...

Medical research

Finding cortisone alternatives with fewer side effects

Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19. Steroidal medication such as cortisone is highly effective but also possesses severe side effects. ...

Genetics

RNA as a future cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production. Patients suffering from a rare hereditary disease that causes a painful ...

Medical research

Seeing corneal degeneration in a new light

The molecular changes that lead to Fuchs' endothelial corneal dystrophy (FECD) occur decades before the disease causes blurry vision and other noticeable symptoms in patients, new research by UT Southwestern scientists shows. ...

Medical research

Unanticipated response to estrogen at the single cell level

A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as ...

Medical research

Researchers develop new database of druggable fusion targets

When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play ...

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