PLoS Genetics
PLoS Genetics is a peer-reviewed, open-access journal that reflects the interdisciplinary nature of genetics and genomics research by publishing contributions in all areas of biology. The journal is indexed in PubMed Central, PubMed, and ISI Web of Knowledge, and was originally created by Wayne Frankel
Diabetes' genetic underpinnings can vary based on ethnic background, studies say
Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine.
Diabetes
May 23, 2013 |
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Recently published research targets malaria mosquito control woes
(Medical Xpress)—Malaria is responsible for about 700,000 deaths annually in sub-Saharan Africa alone, and a team of Texas A&M University researchers is doing their best to help stem this perpetual tide of human suffering.
Genetics
May 07, 2013 |
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With two new methods, scientists hope to improve genome-wide association studies
As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...
Genetics
Apr 26, 2013 |
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Effect of medication is affected by copies of genetic information
The results may help to explain why certain medications have strong side effects on sperm and eggs, and why certain organisms remain unaffected by environmental changes. This is shown by studies that researchers from the ...
Genetics
Apr 10, 2013 |
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Measuring enzyme levels in cancer patients may reveal healthy cells' ability to survive chemotherapy
New research from MIT may allow scientists to develop a test that can predict the severity of side effects of some common chemotherapy agents in individual patients, allowing doctors to tailor treatments ...
Genetics
Apr 05, 2013 |
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New DNA sequences hone in on breast, ovarian cancer risk
Researchers at Mayo Clinic Cancer Center have identified new DNA sequences associated with breast cancer—the most common cancer among women, with an average risk of developing the disease of 10 percent—and ovarian cancer, ...
Cancer
Mar 27, 2013 |
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Scientists find new gene markers for cancer risk
A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...
Genetics
Mar 27, 2013 |
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Study identifies multiple genetic factors impacting development of nearsightedness
In the largest ever genome-wide association study on myopia, 23andMe, the leading personal genetics company, identified 20 new genetic associations for myopia, or nearsightedness. The company also replicated two known associations ...
Genetics
Mar 14, 2013 |
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Zeroing in on heart disease: Innovative strategy pinpoints genes underlying cardiovascular disease risk
Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease. Researchers ...
Genetics
Feb 28, 2013 |
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Pathway controlling cell growth revealed
A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state.
Cancer
Feb 18, 2013 |
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Researchers create new air sacs in mouse model of emphysema using novel growth factor
In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead ...
Medical research
Feb 14, 2013 |
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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans
Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...
Genetics
Feb 07, 2013 |
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Diabetic fruit flies support buzz about dietary sugar dangers
Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at San ...
Genetics
Jan 17, 2013 |
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Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer ...
Genetics
Jan 10, 2013 |
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A history lesson from genes: Using DNA to tell us how populations change
When Charles Darwin first sketched how species evolved by natural selection, he drew what looked like a tree. The diagram started at a central point with a common ancestor, then the lines spread apart as ...
Genetics
Jan 09, 2013 |
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