Proceedings of the National Academy of Sciences

Scientists revisit biochemical basis for depression

Symptoms of depression and anxiety can be induced in mice by increasing levels of acetylcholine, suggesting that depression may have different biochemical roots than previously believed, Yale School of Medicine ...

Medical research created Feb 12, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

One-two punch strategy against bacteria and cancer

Cancer researchers from Rice University suggest that a new man-made drug that's already proven effective at killing cancer and drug-resistant bacteria could best deliver its knockout blow when used in combination ...

Cancer created Feb 11, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Genes for autism and schizophrenia only active in developing brains

Genes linked to autism and schizophrenia are only switched on during the early stages of brain development, according to a study in mice led by researchers at the University of Oxford.

Genetics created Feb 11, 2013 | popularity 3.4 / 5 (30) | comments 0 | with audio podcast

Researchers identify new strategy for interfering with potent cancer-causing gene

Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...

Cancer created Feb 11, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Potential treatment prevents damage from prolonged seizures

A new type of prophylactic treatment for brain injury following prolonged epileptic seizures has been developed by Emory University School of Medicine investigators.

Neuroscience created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Unchecked antibiotic use in animals may affect global human health

The increasing production and use of antibiotics, about half of which is used in animal production, is mirrored by the growing number of antibiotic resistance genes, or ARGs, effectively reducing antibiotics' ability to fend ...

Medical research created Feb 11, 2013 | popularity 4.4 / 5 (7) | comments 3 | with audio podcast

Stem cell discovery gives insight into motor neurone disease

A discovery using stem cells from a patient with motor neurone disease could help research into treatments for the condition. The study used a patient's skin cells to create motor neurons - nerve cells that control muscle ...

Diseases, Conditions, Syndromes created Feb 11, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Mouse models fail to reproduce inflammatory genomic response to serious injuries

Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition.

Inflammatory disorders created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers use new molecular inhibitors to successfully hit difficult cancer target

Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.

Cancer created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Human memory study adds to global debate

(Medical Xpress)—An international study involving researchers from the University of Adelaide has made a major contribution to the ongoing scientific debate about how processes in the human brain support ...

Neuroscience created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists find key element of lupus, suggesting better drug targets

A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The ...

Medical research created Feb 04, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Chemical reaction keeps stroke-damaged brain from repairing itself

Nitric oxide, a gaseous molecule produced in the brain, can damage neurons. When the brain produces too much nitric oxide, it contributes to the severity and progression of stroke and neurodegenerative diseases ...

Medical research created Feb 04, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Some cancer mutations slow tumor growth

A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits ...

Cancer created Feb 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Damaged blood vessels loaded with amyloid worsen cognitive impairment in Alzheimer's disease

A team of researchers at Weill Cornell Medical College has discovered that amyloid peptides are harmful to the blood vessels that supply the brain with blood in Alzheimer's disease—thus accelerating cognitive decline by ...

Alzheimer's disease & dementia created Feb 04, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Injection-free vaccination technique could address global vaccine challenge for HIV, malaria

Scientists at King's College London have demonstrated the ability to deliver a dried live vaccine to the skin without a traditional needle, and shown for the first time that this technique is powerful enough to enable specialised ...

Medical research created Feb 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast