New test distinguishes between two cancers

February 13, 2007

U.S. scientists have created a two-gene test to distinguish between nearly identical gastrointestinal cancers requiring radically different treatments.

"This simple and accurate test has the potential to be relatively quickly implemented in the clinic to benefit patients by guiding appropriate treatment," said senior author Wei Zhang, a professor of pathology at the University of Texas M. D. Anderson Cancer Center.

Researchers say the analytical technique they created to identify gastrointestinal stromal tumor from leiomyosarcoma with near-perfect accuracy will have wider application in more individualized diagnosis and treatment of other types of cancer.

Zhang and his colleagues at the Institute for Systems Biology in Seattle note an existing test distinguishes among the two cancers with about 87 percent accuracy but intensive and time-consuming additional analyses are required for uncertain cases.

The study is reported in the online early edition of the Proceedings of the National Academy of Sciences.

Copyright 2007 by United Press International

Explore further: Genomic testing could speed research on skin disease and bring new drugs to patients faster

Related Stories

Scientists develop MRI-guided neural stem cell delivery method

October 18, 2016

A national science publication has featured the work of San Antonio scientists aiming to develop a more effective method for delivering neural stem cells to the brain in an effort to move forward stem cell therapies to treat ...

Recommended for you

Fighting cancer with the power of immunity

October 24, 2016

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.