Early research shows dietary supplement may lower risk of developing type 2 diabetes

UCLA researchers demonstrated that an over-the-counter dietary supplement may help inhibit development of insulin resistance and glucose intolerance, conditions that are involved in the development of Type 2 diabetes and metabolic syndrome, which affect millions worldwide.

In this early preclinical study, a naturally produced amino acid-like molecule called GABA was given orally to mice that were obese, insulin resistant and in the early stages of Type 2 diabetes. Researchers found that GABA suppressed the inflammatory immune responses that are involved in the development of this condition.

According to study authors, GABA helped prevent disease progression and improved and insulin sensitivity, even after onset of Type 2 diabetes in mice. Researchers also identified the regulatory immune cells that likely direct GABA's activity in inhibiting inflammation.

More information: The research appears in the Sept. 22 online edition of the peer-reviewed journal, PLoS One.

Provided by University of California - Los Angeles

5 /5 (4 votes)
add to favorites email to friend print save as pdf

Related Stories

AAT protein restores blood glucose in type 1 diabetes model

Oct 14, 2008

A protein made by the liver in response to inflammation and used to treat patients suffering from a genetic form of emphysema has been shown to restore blood glucose levels in a mouse model of Type 1 diabetes mellitus, according ...

Recommended for you

Ebola fears infect Louisiana medical conference

18 minutes ago

Ebola fears have infected a U.S. medical conference on the subject. Louisiana state health officials told thousands of doctors planning to attend a tropical diseases meeting this weekend in New Orleans to stay away if they ...

Experts urge caution over Ebola hopes (Update)

5 hours ago

Health authorities called Thursday for renewed vigilance over the Ebola epidemic, urging caution over claims that the outbreak is retreating as the World Bank boosted the global response with $100 million for health workers.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.