Autism Speaks and BGI to complete whole genome sequencing on 10,000 with autism
Autism Speaks, the world's largest autism science and advocacy organization, and BGI, the largest genomic organization in the world and a global leader in whole genome sequencing, jointly announce their partnership to create the world's largest library of sequenced genomes of individuals with autism spectrum disorders (ASD). Using the Autism Speaks Autism Genetic Resource Exchange (AGRE), this collaboration will perform whole genome sequencing on more than 2,000 participating families who have two or more children on the autism spectrum. The data from the 10,000 AGRE participants will enable new research in the genomics of ASD, and significantly enhance the science and technology networks of both Autism Speaks and BGI. In addition, Autism Speaks and BGI will collect and sequence genome samples from individuals in China.
"This collaboration will transform the field and greatly accelerate basic and translational research in autism and related developmental disabilities," stated Autism Speaks Vice President for Scientific Affairs Andy Shih, Ph.D. "This collection of sequenced genomes will facilitate new collaborations engaging researchers around the world, and enable public and private entities to pursue pivotal research."
The Autism Speaks BGI collaboration will be conducted over a two-year period. The initial pilot sequencing of 100 genomes will be directly funded by the Autism Speaks science portfolio. Additional funding will be secured from government, donors, and public and private sources.
"We welcome the opportunity to collaborate with Autism Speaks on this groundbreaking research project," stated Prof. Yang Huanming, Chairman of BGI. "Having sequenced more than 10,000 whole human genomes to date, and given our state-of-the-art sequencing and bioinformatics technologies, we are excited about the potential to have a meaningful impact on advancing new treatments for autism spectrum disorder."
"Piece by piece, we are discovering genetic mutations that can cause autism and we have learned from examples involving single gene disorders associated with autism, such as Fragile X and Rett Syndrome, that genetic findings substantially increase our understanding of the underlying biology of autism," said Geraldine Dawson, Ph.D., Autism Speaks chief science officer. "Our ultimate goal is for the information we will gain from whole genome sequencing to contribute to the development of novel effective treatments to improve the lives of individuals impacted by autism."
Provided by Autism Speaks
-
Mortality rate is increased in persons with autism who also have epilepsy
Apr 15, 2011 |
not rated yet |
0
-
Genetic finding identifies male-linked mutation associated with autism spectrum disorders
Sep 15, 2010 |
not rated yet |
0
-
Risk of autism among younger siblings of a child with autism much greater than previously reported
Aug 15, 2011 |
not rated yet |
0
-
Researchers report new autism genes discovered
Jun 09, 2010 |
not rated yet |
0
-
Hopkins researchers release genome data on autism
Oct 23, 2007 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011
- More from Physics Forums - Independent Research
More news stories
Researchers identify new circadian clock component
Northwestern University scientists have shown a gene involved in neurodegenerative disease also plays a critical role in the proper function of the circadian clock.
Genetics
May 16, 2013 |
3 / 5 (1) |
1
|
Returning genetic incidental findings without patient consent violates basic rights, experts say
Informed consent is the backbone of patient care. Genetic testing has long required patient consent and patients have had a "right not to know" the results. However, as 21st century medicine now begins to use the tools of ...
Genetics
May 16, 2013 |
5 / 5 (1) |
3
|
Ethicists provide framework supporting new recommendations on reporting incidental findings in gene sequencing
In a paper published in Science Express, a group of experts led by bioethicists in the Center for Medical Ethics and Health Policy at Baylor College of Medicine provide a framework for the new American College of Medical Geneti ...
Genetics
May 16, 2013 |
not rated yet |
0
Experts urge caution over use of new genetic sequencing techniques
The use of genome-wide analysis (GWA), where the entirety of an individual's DNA is examined to look for the genomic mutations or variants which can cause health problems is a massively useful technology for diagnosing disease. ...
Genetics
May 16, 2013 |
not rated yet |
0
Collecting DNA for human rights: How to help while safeguarding privacy
DNA databases might help identify victims of crime and human trafficking, but how do we safeguard the personal privacy of innocent victims and family members? A new report online May 15 in the Cell Press journal Trends in ...
Genetics
May 15, 2013 |
not rated yet |
0
Neurons that can multitask greatly enhance the brain's computational power, study finds
Over the past few decades, neuroscientists have made much progress in mapping the brain by deciphering the functions of individual neurons that perform very specific tasks, such as recognizing the location ...
Anabolic steroids may affect future mental health
There is a link between use of anabolic-androgenic steroids and reduced mental health later in life. This is the main conclusion of a new study on elite male strength athletes that researchers from the University of Gothenburg ...
Half time warm-ups boost athletic performance
High-intensity, short duration warm up activities at half time intervals boost athletic performance, a study of soccer players has found.
Youth bullying because of perceived sexual orientation widespread and damaging
(Medical Xpress)—Bullying because of perceived sexual orientation is prevalent among school-aged youths, according to a study led by Donald Patrick, professor of health services at the UW School of Public ...
Study finds improved CPR quality saves lives
(Medical Xpress)—Life-saving CPR has been a foundation of emergency medicine for more than a half century. But researchers at the University of Arizona College of Medicine-Phoenix are continuing to refine the procedure, ...
Team finds mechanism linking key inflammatory marker to cancer
In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.