Automatic suspension of insulin delivery via insulin pumps reduces hypoglycemia

An automated on/off feature built into insulin pump systems can suspend insulin delivery when it detects low blood glucose levels (via continuous glucose monitoring), significantly reducing the severity and duration of hypoglycemia in individuals with type 1 diabetes, according to a study published in Diabetes Technology & Therapeutics.

In the study, Satish Garg, MD, Editor-in-Chief of Diabetes Technology & Therapeutics and Professor of Medicine and Pediatrics at the University of Colorado Denver, and colleagues from the Barbara Davis Center for Childhood Diabetes (Aurora, CO), Rainier Clinical Research Center (Renten, WA), AMCR Institute, Inc. (Escondido, CA), Stanford University Medical Center (CA), Mills-Peninsula Health Services (San Mateo, CA), and Medtronic Inc. (Northridge, CA) used a regimen of fasting and exercise to induce hypoglycemia in a group of subjects with type 1 diabetes who use insulin pump delivery devices along with continuous .

They compared the severity and duration of hypoglycemia and the risk of rebound hyperglycemia when the automated "low glucose suspend" feature of the pump was turned on or off. They report their findings in the article "Reduction in Duration of Hypoglycemia by Automatic Suspension of : The In-Clinic ASPIRE Study."

"This is the first randomized cross-over trial with an attempt to develop an artificial pancreas," says Dr. Garg.

Provided by Mary Ann Liebert, Inc.

not rated yet
add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Dialysis patients may have faulty 'good' cholesterol

9 hours ago

Kidney disease patients on dialysis often have impaired high-density lipoprotein (HDL) or "good" cholesterol, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN) ...

Freshwater algae can infect wounds, study shows

11 hours ago

(HealthDay)—The cases of two men who got injured while enjoying the great outdoors in Missouri and Texas are giving insight into a freshwater algae that can infect wounds.

Biomarker for fatty liver disease

18 hours ago

40 percent of people in the EU suffer from non-alcoholic steatohepatitis (fatty liver disease), a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.