Staph sepsis increases mortality in preterm infants

Staph sepsis increases mortality in preterm infants

(HealthDay) -- Only about 1 percent of very low birth weight (VLBW) infants develop methicillin-resistant Staphylococcus aureus (MRSA) infections, and the morbidity and mortality are similar to that seen in infants with methicillin-susceptible S. aureus (MSSA) infections, according to a study published online March 12 in Pediatrics.

Andi L. Shane, M.D., M.P.H., from the Emory University School of Medicine in Atlanta, and colleagues analyzed data on morbidity and mortality for 8,444 VLBW infants (birth weight, 401 to 1,500 g), of whom 316 (3.7 percent) had S. aureus bacteremia and/or meningitis.

The researchers found that 88 of the 316 cases (28 percent) were MRSA and 228 cases (72 percent) were MSSA, with no overlap. The two groups were similar in terms of morbidities such as the need for , diagnosis of , and necrotizing enterocolitis. Nearly all (99 percent) of occurred >72 hours after birth. Mortality was high but similar in the resistant and susceptible groups (26 versus 24 percent).

"Few VLBW infants had S. aureus bacteremia and/or meningitis. The 1 percent with MRSA had morbidity and mortality rates similar to infants with MSSA," Shane and colleagues conclude. "Practices should provide equal focus on prevention and management of both MRSA and MSSA infections among VLBW infants."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

MRSA head and neck infections increase among children

Jan 19, 2009

Rates of antibiotic-resistant head and neck infections increased in pediatric patients nationwide between 2001 and 2006, according to a report in the January issue of Archives of Otolaryngology-Head & Neck Surgery, one of ...

Study finds MRSA danger in gyms may be exaggerated

Mar 03, 2011

Community gym surfaces do not appear to be reservoirs for MRSA transmission, according to a study published in the March issue of the American Journal of Infection Control, the official publication of APIC – the Associ ...

Recommended for you

Ebola death toll rises to 5,459: WHO

1 hour ago

The World Health Organization said Friday that 5,459 people had so far died of Ebola out of a total 15,351 cases of infection in eight countries since late December 2013.

Flu season off to a slow start ... for now

4 hours ago

(HealthDay)—This year's flu season is off to a slow but detectable start. And it appears to be a typical one that's likely to peak in January or February, a leading U.S. health official says.

Update on new treatments for liver diseases

5 hours ago

Cirrhosis and nonalcoholic fatty liver disease (NAFLD) are two serious liver conditions with limited pharmacological treatments. The December issues of AGA's journals—Clinical Gastroenterology and Hepatology and Gastro ...

Amateur photographers aid in remote skin sore trial

6 hours ago

Paediatric infectious disease specialists are bringing novel skin sore research methods to WA in the form of a protocol allowing non-professional photographers to capture high-quality images of skin sores ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.