Isomaltulose doesn't improve glycemic control in diabetes

Isomaltulose doesn't improve glycemic control in diabetes

(HealthDay) -- For patients with type 2 diabetes, substitution of sucrose with isomaltulose is not associated with improved glycemic control (measured by hemoglobin A1c [HbA1c] levels) at 12 weeks, according to a study published online April 9 in Diabetes Care.

Stefanie Brunner, from the Technische Universität München in Munich, Germany, and colleagues investigated whether replacement of sucrose with isomaltulose in sweet foods and drinks would improve metabolic control in . A total of 110 patients with type 2 diabetes were randomly allocated to receive sweet foods containing 50 g per day of isomaltulose or sucrose for 12 weeks as part of their habitual diet. The primary outcome parameter was HbA1c at 12 weeks.

In the final analysis of 101 patients, the researchers found that isomaltulose had no significant effect on HbA1c at 12 weeks. Compared with the sucrose group, in the isomaltulose group, triglycerides were significantly lower at 12 weeks. There was no difference in any other secondary parameters.

"Substitution of 50 g/day sucrose by isomaltulose in sweet food and beverages over 12 weeks did not significantly affect HbA1c and most other metabolic and cardiovascular risk parameters," the authors write. "Although the principle of isomaltulose action is unquestionable, a more marked modification of the dietary glycemic index may be required to achieve a clinically significant improvement in in type 2 diabetic patients."

Several of the authors disclosed financial ties to Suedzucker AG, which funded the study.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Study assesses glucose monitoring trends in tweens

Apr 12, 2012

(HealthDay) -- During the transition to adolescence, children with type 1 diabetes monitor their blood glucose less frequently, resulting in significant increases in HbA1c levels, according to research published ...

Bolus calculation, flexible insulin up diabetes control

Feb 24, 2012

(HealthDay) -- A structured course teaching the benefits of automated bolus calculator (ABC) use and flexible intensive insulin therapy (FIIT) improves metabolic control and satisfaction in patients with type ...

Recommended for you

Low-carb diet recommended for diabetics

Jul 29, 2014

A new study involving researchers from the University of Alabama at Birmingham and other institutions says patients with Type 1 and Type 2 diabetes should eat a diet low in carbohydrates.

Shift work linked to heightened risk of type 2 diabetes

Jul 24, 2014

Shift work is linked to a heightened risk of developing type 2 diabetes, with the risk seemingly greatest among men and those working rotating shift patterns, indicates an analysis of the available evidence published online ...

Rosemary and oregano contain diabetes-fighting compounds

Jul 23, 2014

The popular culinary herbs oregano and rosemary are packed with healthful compounds, and now lab tests show they could work in much the same way as prescription anti-diabetic medication, scientists report. In their new study ...

User comments