Isomaltulose doesn't improve glycemic control in diabetes
(HealthDay) -- For patients with type 2 diabetes, substitution of sucrose with isomaltulose is not associated with improved glycemic control (measured by hemoglobin A1c [HbA1c] levels) at 12 weeks, according to a study published online April 9 in Diabetes Care.
Stefanie Brunner, from the Technische Universität München in Munich, Germany, and colleagues investigated whether replacement of sucrose with isomaltulose in sweet foods and drinks would improve metabolic control in type 2 diabetes. A total of 110 patients with type 2 diabetes were randomly allocated to receive sweet foods containing 50 g per day of isomaltulose or sucrose for 12 weeks as part of their habitual diet. The primary outcome parameter was HbA1c at 12 weeks.
In the final analysis of 101 patients, the researchers found that isomaltulose had no significant effect on HbA1c at 12 weeks. Compared with the sucrose group, in the isomaltulose group, triglycerides were significantly lower at 12 weeks. There was no difference in any other secondary parameters.
"Substitution of 50 g/day sucrose by isomaltulose in sweet food and beverages over 12 weeks did not significantly affect HbA1c and most other metabolic and cardiovascular risk parameters," the authors write. "Although the principle of isomaltulose action is unquestionable, a more marked modification of the dietary glycemic index may be required to achieve a clinically significant improvement in glycemic control in type 2 diabetic patients."
Several of the authors disclosed financial ties to Suedzucker AG, which funded the study.
More information: Abstract
Full Text (subscription or payment may be required)
Copyright © 2012 HealthDay. All rights reserved.
-
Study assesses glucose monitoring trends in tweens
Apr 12, 2012 |
not rated yet |
0
-
Low-glycemic diet shows greater improvement in glycemic control than high-fiber diet
Dec 17, 2008 |
not rated yet |
0
-
Structured exercise training associated with improved glycemic control for patients with diabetes
May 03, 2011 |
not rated yet |
0
-
Bolus calculation, flexible insulin up diabetes control
Feb 24, 2012 |
not rated yet |
0
-
Low glycemic diet better for glycemic control of type 2 diabetes than whole grains
Dec 18, 2008 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
Learning curve of Electromagnetism?
3 hours ago
-
thin glass in liquid
4 hours ago
-
How many joules expended for a push up?
7 hours ago
-
force to keep the folding doors
7 hours ago
-
Confusion regarding direction of kinetic friction on inclined plane.
8 hours ago
-
Mage hand
14 hours ago
- More from Physics Forums - Classical Physics
More news stories
Exercise prevents fructose-induced hypertriglyceridemia
(HealthDay)—Moderate aerobic exercise prevents fructose-induced hypertriglyceridemia in healthy males, according to a study published online May 14 in Diabetes.
Diabetes
May 17, 2013 |
5 / 5 (1) |
0
|
DNA variant affects diabetes risk and treatment response
A DNA variant near a digestive enzyme does not only affect risk of developing diabetes but also affects the response to treatment, an international consortium of researchers including the University of Dundee has found.
Diabetes
May 17, 2013 |
not rated yet |
0
|
The artificial pancreas that keeps tabs on sugar
(Medical Xpress)—Development of a sophisticated artificial pancreas holds potential to transform the lives of patients with Type 1 diabetes.
Diabetes
May 16, 2013 |
5 / 5 (1) |
0
|
Study findings significant for treating infections in Type 1 diabetes
A small University at Buffalo study has found for the first time that in Type 1 diabetics, insulin injections exert a strong anti-inflammatory effect at the cellular and molecular level, while even small amounts of glucose ...
Diabetes
May 16, 2013 |
not rated yet |
0
Hospital hypoglycemia rates up in black men with diabetes
(HealthDay)—Home diabetes regimens partially explain the increased risk of having a hypoglycemia event during hospitalization among older African-American men with diabetes, according to a study published ...
Diabetes
May 14, 2013 |
not rated yet |
0
New research identifies risks, interventions for children's GI health
An increasing number of U.S. children are experiencing gastrointestinal issues that require interventions to resolve, according to research presented at Digestive Disease Week (DDW).
AIDS science at 30: 'Cure' now part of lexicon
Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.
For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests
Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brain regions can over-or ...
US psychiatry gets makeover in new manual
The latest makeover to a massive psychiatric tome honored by some, reviled by others and even called the "Bible" of mental disorders is being released Saturday with a host of new changes.
New case of SARS-like virus in Saudi: ministry
A new case of the deadly coronavirus has been detected in Saudi Arabia where 15 people have already died after contracting it, the health ministry announced on Saturday on its Internet website.
New colonoscope provides ground-breaking view of colon
A ground-breaking advance in colonoscopy technology signals the future of colorectal care, according to research presented today at Digestive Disease Week(DDW). Additional research focuses on optimizing the minimal withdrawal ...