Early vaccinations not linked to celiac disease in sweden

June 25, 2012 in Diseases, Conditions, Syndromes

Early vaccinations not linked to celiac disease in sweden

Early vaccinations do not seem to influence the risk of celiac disease among infants, nor do changes in the vaccination program explain the celiac disease epidemic, according to a Swedish study published online June 25 in Pediatrics.

(HealthDay) -- Early vaccinations do not seem to influence the risk of celiac disease (CD) among infants, nor do changes in the vaccination program explain the CD epidemic, according to a Swedish study published online June 25 in Pediatrics.

To investigate whether changes in the national Swedish coincided with changes in the incidence of CD in infants, Anna Myléus, Ph.D., M.D., from Umeå University in Sweden, and colleagues analyzed data from the National Swedish Childhood Register and performed a population-based incident case-referent study of infants. Questionnaires and child health clinic records were used to obtain exposure information. The responses to the following vaccines were examined: diphtheria/tetanus, pertussis (acellular), polio (inactivated), Haemophilus influenza type b (conjugated), measles/ mumps/rubella, and live attenuated bacillus Calmette-Guérin (BCG; given to children with increased tuberculosis risk).

The researchers found that the introduction of the pertussis vaccine coincided in time with decreasing CD incidence rates, but there was no association seen between CD and vaccination against pertussis (odds ratio, 0.91; 95 percent confidence interval, 0.60 to 1.4), Haemophilus influenza type b, or measles/mumps/rubella. BCG correlated with decreased risk for CD (adjusted odds ratio, 0.54), but discontinuation of general BCG vaccination had no impact on the cumulative incidence of CD at age 15 years.

"The Swedish epidemic of CD is not fully understood, and changes in the vaccination program or coverage do not contribute to the explanation," the authors write. "We found no epidemiologic evidence that the immunologic response to increases CD risk."

Abstract

Full Text (subscription or payment may be required)

Journal reference: Pediatrics search and more info website

Copyright © 2012 HealthDay. All rights reserved.

not rated yet  

Rank not rated yet
Relevant PhysicsForums posts

More news stories

FDA warns of infections tied to Tennessee pharmacy

(AP)—Government health officials are investigating several health problems reported with potentially contaminated medications made by a Tennessee specialty pharmacy.

Diseases, Conditions, Syndromes created 2 minutes ago | popularity not rated yet | comments 0

Comorbidities common with alopecia areata

(HealthDay)—Comorbid conditions often accompany alopecia areata, according to a study published online May 22 in JAMA Dermatology.

Diseases, Conditions, Syndromes created 1 hour ago | popularity not rated yet | comments 0

Top-ranked golfer beats scoliosis

(HealthDay)—As a world-class golfer, Stacy Lewis' accomplishments are remarkable. But it was a physical challenge in her childhood that defined her ascent to the top of her sport.

Diseases, Conditions, Syndromes created 1 hour ago | popularity not rated yet | comments 0

Saudi to send animal samples to US in coronavirus probe (Update)

Saudi Arabia said Friday it would send samples taken from animals possibly infected with a deadly SARS-like virus to the United States for testing in a bid to find the source of disease.

Diseases, Conditions, Syndromes created 4 hours ago | popularity not rated yet | comments 0

WHO voices deep concern over spread of SARS-like virus

The World Health Organization voiced deep concern Thursday over the SARS-like virus that has killed 22 people in less than a year, saying it might potentially spread more widely between humans.

Diseases, Conditions, Syndromes created 8 hours ago | popularity 5 / 5 (1) | comments 0


Researchers identify first drug targets in childhood genetic tumor disorder

Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...

Pollen count apps for smartphones are nothing to sneeze at

Kate O'Reilly's spring allergy survival kit includes the usual stuff - nasal sprays, allergy pills and a box of tissues. This season, she's added a new weapon to her line of defense: an app on her smartphone.

Engineered cytomegalovirus protects monkeys from HIV equivalent

(Medical Xpress)—A new study by researchers in the US has shown that an ancient virus can be modified to help in the fight against the simian immunodeficiency virus SIV, which is the equivalent in monkeys ...

Hormone levels may provide key to understanding psychological disorders in women

Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.

Going live: Immune cell activation in multiple sclerosis

Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...

ACOG: Hormone therapy not recommended to prevent CHD

(HealthDay)—Menopausal hormone therapy should not be used for prevention of coronary heart disease, according to a Committee Opinion from the American College of Obstetricians and Gynecologists (ACOG) published ...