In preemies, maternal smoking tied to necrotizing enterocolitis

In preemies, maternal smoking tied to necrotizing enterocolitis
Maternal smoking has been identified as a risk factor associated with the development of necrotizing enterocolitis in premature infants, according to a study published June 11 in Pediatrics.

(HealthDay) -- Maternal smoking has been identified as a risk factor associated with the development of necrotizing enterocolitis (NEC) in premature infants, according to a study published June 11 in Pediatrics.

Cynthia D. Downard, M.D., from the University of Louisville in Kentucky, and colleagues reviewed the medical records of infants with NEC identified from a unit database as well as the prenatal and delivery record of the patient's mother. Each of 73 neonates with NEC was matched to two neonate controls who were treated at the same institution.

The researchers found that maternal cigarette smoking correlated significantly with the development of NEC (P = 0.02). There was no correlation seen between maternal gestational diabetes, maternal hypertension, formula feeding, and pathologic chorioamnionitis or uteroplacental insufficiency and NEC.

"These data identified maternal cigarette smoking as the only risk factor that is associated with the development of NEC in premature infants," the authors write. "Our data imply that smoking delivers toxins and nicotine to the uterine microenvironment that can affect microvascular development and may predispose the fetus to future NEC."

The study was funded by the James R. Petersdorf Fund of Norton Healthcare.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Brain abnormality found in group of SIDS cases

16 hours ago

More than 40 percent of infants in a group who died of sudden infant death syndrome (SIDS) were found to have an abnormality in a key part of the brain, researchers report. The abnormality affects the hippocampus, ...

Eczema cases rising among US children

Nov 24, 2014

(HealthDay)—A growing number of children are being diagnosed with the allergic skin condition eczema—but it can usually be eased with topical treatments, according to a new report.

Adult-sized ATVs deadly for kids, report shows

Nov 24, 2014

(HealthDay)—Santa might think twice about giving kids an all-terrain vehicle this year. Riding ATVs poses high risks of injury or death for children and teens, with dangers differing by age, a new U.S. ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.